1269429-14-2

Upstream product

• 1269429-13-1 methyl 4-[(5R,6R)-5-amino-6-{[tert-butyl(dimethyl)silyl]oxy}-6-(6-chloropyridin-3-yl)hex-1-yn-1-yl]benzoate 
• 1269429-12-0 methyl 4-[(5R,6R)-6-{[tert-butyl(dimethyl)silyl]oxy}-6-(6-chloropyridin-3-yl)-5-({[(4-methoxybenzyl)oxy]carbonyl}amino)hex-1-yn-1-yl]benzoate 
• 1190614-94-8 4-methoxybenzyl ((1R,2R)-1-((tert-butyldimethylsilyl)oxy)-1-(6-chloropyridin-3-yl)hex-5-yn-2-yl)carbamate 
• 1190614-98-2 (R)-2-((S)-(6-chloropyridin-3-yl)((trimethylsilyl)oxy)methyl)hex-5-ynoic acid 
• 1190614-97-1 (S)-4-benzyl-3-((R)-2-((S)-(6-chloropyridin-3-yl)((trimethylsilyl)oxy)methyl)hex-5-ynoyl)oxazolidin-2-one 
• 1190614-96-0 (S)-4-benzyl-3-((R)-2-((S)-(6-chloropyridin-3-yl)(hydroxy)methyl)hex-5-ynoyl)oxazolidin-2-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1269429-42-6 C₂₅H₃₅ClN₂O₃Si 

Downstream Products

• 1269615-53-3 tert-butyl (2R,5S)-2-[(R)-{[tert-butyl(dimethyl)silyl]oxy}(1-oxidopyridin-3-yl)methyl]-5-[4-(methoxycarbonyl)benzyl]pyrrolidine-1-carboxylate 
• 1269615-32-8 tert-butyl (2R,5S)-2-[(R)-{[tert-butyl(dimethyl)silyl]oxy}{6-[(2-phenylpropan-2-yl)amino]pyridin-3-yl}methyl]-5-[4-(methoxycarbonyl)benzyl]pyrrolidine-1-carboxylate 
• 1269615-31-7 4-({(2S,5R)-1-(tert-butoxycarbonyl)-5-[(R)-{[tert-butyl(dimethyl)silyl]oxy}{6-[(2-phenylpropan-2-yl)amino]pyridin-3-yl}methyl]pyrrolidin-2-yl}methyl)benzoic acid 
• 1269615-35-1 tert-butyl (2R,5S)-2-[(R)-[6-(tert-butylamino)pyridin-3-yl]{[tert-butyl(dimethyl)silyl]oxy}methyl]-5-[4-(methoxycarbonyl)benzyl]pyrrolidine-1-carboxylate 
• 1269615-36-2 tert-butyl (2R,5S)-2-[(R)-[6-(tert-butylamino)pyridin-3-yl](hydroxy)methyl]-5-[4-(methoxycarbonyl)benzyl]pyrrolidine-1-carboxylate 
• 1269615-37-3 4-({(2S,5R)-1-(tert-butoxycarbonyl)-5-[(R)-[6-(tert-butylamino)pyridin-3-yl](hydroxy)methyl]pyrrolidin-2-yl}methyl)benzoic acid 
• 1269615-38-4 tert-butyl (2R,5S)-2-[(R)-[6-(tert-butylamino)pyridin-3-yl](hydroxy)methyl]-5-[4-(dimethylcarbamoyl)benzyl]pyrrolidine-1-carboxylate 
• 1269429-18-6 (2R,5S)-tert-butyl-2-((R)-((tert-butyldimethylsilyl)oxy)(pyridin-3-yl)methyl)-5-(4-(methoxycarbonyl)benzyl)pyrrolidine-1-carboxylate 
• 1269429-11-9 4-(((2S,5R)-1-(tert-butoxycarbonyl)-5-((R)-((tert-butyldimethylsilyl)oxy)(pyridin-3-yl)methyl)pyrrolidin-2-yl)methyl)benzoic acid 
• 1269429-20-0 tert-butyl (2R,5S)-2-[(R)-hydroxy(pyridin-3-yl)methyl]-5-[4-(methoxycarbonyl)benzyl]pyrrolidine-1-carboxylate 
• 1269429-19-7 4-({(2S,5R)-1-(tert-butoxycarbonyl)-5-[(R)-hydroxy(pyridin-3-yl)methyl]pyrrolidin-2-yl}methyl)benzoic acid 

Relevant academic research and scientific papers

NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS

The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.