1269440-49-4

Usage

Uses

Used in Organic Synthesis:
1-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)ethanone is used as a key intermediate in organic synthesis for the creation of complex organic molecules. Its unique structure allows for versatile chemical reactions, facilitating the development of novel compounds with diverse applications.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)ethanone is used as a starting material for the development of new drugs. Its potential applications in the creation of pharmaceuticals and agrochemicals are attributed to its ability to be modified and incorporated into various molecular frameworks, potentially leading to the discovery of new therapeutic agents.
Used in the Study of Organic Reaction Mechanisms:
1-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)ethanone is also utilized in academic and research settings to investigate the mechanisms of organic reactions. Understanding how 1-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)ethanone reacts with other chemicals can provide insights into reaction pathways and help in the design of more efficient synthetic routes for the production of desired compounds.

Upstream product

• 1269440-48-3 1-(3-amino-1-isopropyl-1H-pyrazol-4-yl)ethanone 
• 97619-92-6 2-((2-benzylidene-1-isopropylhydrazinyl)methylene)malononitrile 
• 89897-29-0 3-amino-1-isopropyl-1H-pyrazole-4-carbonitrile 

Downstream Products

• 1269440-15-4 methyl N-[(2S)-1-[(4-{3-[2,6-difluoro-3-(propane-1-sulfonamido)phenyl]-1-(propan-2-yl)-1H-pyrazol-4-yl}pyrimidin-2-yl)amino]propan-2-yl]carbamate 
• 1269440-24-5 N-(2,4-difluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propane-1-sulfonamide 
• 1269440-76-7 (S)-methyl 1-(4-(3-(3-amino-2-chloro-5-fluorophenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-ylamino)propan-2-ylcarbamate 
• 1269440-09-6 methyl N-[(2S)-1-[(4-{3-[5-chloro-2-fluoro-3-(propane-1-sulfonamido)phenyl]-1-(propan-2-yl)-1H-pyrazol-4-yl}pyrimidin-2-yl)amino]propan-2-yl]carbamate 
• 1269440-77-8 (S)-methyl 1-(4-(3-(5-chloro-2-fluoro-3-(tert-butoxycarbonylamino)phenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-ylamino)propan-2-ylcarbamate 
• 1269440-78-9 (S)-methyl 1-(4-(3-(3-amino-5-chloro-2-fluorophenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-ylamino)propan-2-ylcarbamate 
• 1269440-99-4 (S)-methyl 1-(4-(3-(5-chloro-2-fluoro-3-(N-(methylsulfonyl)methylsulfonamido)phenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-ylamino)propan-2-ylcarbamate 
• 1269440-58-5 2-chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine 

Relevant academic research and scientific papers

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

The invention provides a novel class of compounds of formula 1, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.