1269464-36-9

Upstream product

• 1269467-99-3 methyl 4-oxo-4,5-dihydrothieno[3,2-c]quinoline-6-carboxylate 
• 1269467-96-0 methyl 2-amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 
• 1269468-25-8 4-chloro-6-(4H-1,2,4-triazol-3-yl)thieno[3,2-c]quinoline 
• 2106-02-7 2-chloro-4-fluoroaniline 
• 1269468-24-7 6-(4H-1,2,4-triazol-3-yl)thieno[3,2-c]quinolin-4(5H)-one 
• 1269468-22-5 4-oxo-4,5-dihydrothieno[3.2-c]quinoline-6-carboxarnide 
• 1269468-20-3 4-oxo-4,5-dihydrothieno[3.2-c]quinoline-6-carboxylic acid 

Relevant academic research and scientific papers

Novel potent dual inhibitors of CK2 and Pim kinases with antiproliferative activity against cancer cells

A novel family of potent dual inhibitors of CK2 and the Pim kinases was discovered by modifying the scaffolds of tricyclic Pim inhibitors. Several analogs were active at single digit nanomolar IC50 values against CK2 and the Pim isoforms Pim-1

CONDENSED QUINOLINES AS PROTEIN KINASE MODULATORS

The invention relates in part to molecules of formula (I) having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. Molecules of the inv