126972-57-4Relevant articles and documents
TANDEM NUCLEOPHILIC SUBSTITUTION - 1,3 DIPOLAR CYCLOADDITION REACTIONS OF OXIMES WITH EPOXIDES AND DIPOLAROPHILES.
Grigg, Ronald,Markandu, Jasothara
, p. 5489 - 5492 (2007/10/02)
Regiospecific nucleophilic substitution reactions involving attack of the nitrogen atom of oximes on epoxides are used to generate nitrones which are then trapped in 1,3-dipolar cycloaddition reactions.These tandem processes are shown to be flexible and to have wide synthetic scope for the construction of complex molecular frameworks.