1269772-29-3

Upstream product

• 3792-04-9 2-chloro-N-[2-(trifluoromethyl)phenyl]acetamide 
• 294-90-6 1,4,7,10-tetraazacyclododecan 

Downstream Products

• 1269772-30-6 1,5-dimethyl (2R)-2-{7-[(2R)-1,5-dimethoxy-1,5-dioxopentan-2-yl]-4,10-bis({[(2-trifluoromethyl)phenyl]carbamoyl}methyl)-1,4,7,10-tetraazacyclododecan-1-yl}pentanedioate 

Relevant academic research and scientific papers

Strategies to enhance signal intensity with paramagnetic fluorine-labelled lanthanide complexes as probes for 19F magnetic resonance

The synthesis and 19F NMR spectroscopic properties are reported for three series of CF3-labelled lanthanide(iii) complexes, based on mono- and diamide cyclen ligands. Analyses of variable temperature, pH and field 19F, 17O and 1H NMR spectroscopic experiments are reported and the merits of a triphosphinate mono-amide complex defined by virtue of its favourable isomer distribution and attractive relaxation properties. These lead to an enhanced sensitivity of detection in 19F magnetic resonance experiments versus a diamagnetic Y(iii) analogue, paving the way for future shift and imaging studies.