1269824-46-5

Upstream product

• 35302-72-8 pyrrol-2-yl trichloromethyl ketone 
• 1269822-93-6 1-(4-acetyl-5-nitro-1H-pyrrol-2-yl)-2,2,2-trichloroethanone 
• 1269822-94-7 methyl 4-acetyl-5-nitro-1H-pyrrole-2-carboxylate 
• 72652-34-7 1-(4-acetyl-1H-pyrrol-2-yl)-2,2,2-trichloroethan-1-one 

Downstream Products

• 1269823-46-2 2-(1-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)cyclohexyl)acetonitrile 
• 1269823-47-3 (4-(1-(1-(cyanomethyl)cyclohexyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate 
• 1269823-53-1 (R)-3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-cyclohexylpropanenitrile 
• 1269823-54-2 (R)-(4-(1-(2-cyano-1-cyclohexylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate 
• 1269823-55-3 (R)-(4-(1-(1-cyclohexyl-3-oxopropyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate 
• 1269823-69-9 2-(7H-pyrrolo[2,3-c]pyridazin-4-yl)aniline 
• 1269822-97-0 7H-pyrrolo[2,3-c]pyridazin-4-ol 
• 1269823-77-9 (R)-3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-phenylpropane nitrile 
• 1269823-78-0 (R)-(4-(1-(2-cyano-1-phenylethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate 
• 1269823-79-1 (R)-(4-(1-(3-oxo-1-phenylpropyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate 
• 1269823-80-4 (R)-3-(4-(7H-pyrrolo[2,3-c]pyridazin-4-yl)-1H-pyrazol-1-yl)-3-(3-hydroxyphenyl)propanenitrile 
• 1269823-81-5 (R)-(4-(1-(2-cyano-1-(3-hydroxyphenyl)ethyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate 
• 1269823-82-6 (R)-(4-(1-(1-(3-hydroxyphenyl)-3-oxopropyl)-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-c]pyridazin-7-yl)methyl pivalate 
• 1269822-95-8 methyl 4-hydroxy-7H-pyrrolo[2,3-c]pyridazine-6-carboxylate 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS AS JANUS KINASE INHIBITORS

The invention provides compounds of formula (I) or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for suppressing an immune response or treating cancer or a hematologic malignancy using compounds of formula (I).