1270020-09-1

Basic information

• Product Name: 4-(4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3,5-bis[2-(aminothioxomethyl)hydrazide]
• Synonyms: 4-(4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3,5-bis[2-(aminothioxomethyl)hydrazide]
• CAS NO: 1270020-09-1
• Molecular Weight: 435.531
• Mol File: 1270020-09-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3,5-bis[2-(aminothioxomethyl)hydrazide](CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3,5-bis[2-(aminothioxomethyl)hydrazide](1270020-09-1)
• EPA Substance Registry System: 4-(4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3,5-bis[2-(aminothioxomethyl)hydrazide](1270020-09-1)

Safety Data

• Hazardous Substances Data: 1270020-09-1(Hazardous Substances Data)

Upstream product

• 10354-30-0 4-(4-hydroxy-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 79-19-6 thiosemicarbazide 
• 123-08-0 4-hydroxy-benzaldehyde 

Relevant articles and documents

Synthesis and anticoagulant activity of a new series of 1,4-dihydropyridine derivatives

A series of 1,4-dihydropyridine derivatives (1a-g) were prepared from three compounds condensation reaction of ethylacetoacetate, aromatic aldehyde and ammonium hydroxide. A new series of compounds (2a-g) were prepared from compounds (1a-g) via reaction with thiosemicarbazide using the condensation method. The synthesized compounds were confirmed by IR, 1H NMR, 13C NMR, mass spectral and elemental analyses. The synthesized compounds (1a-g) and (2a-g) were also screened for anticoagulant properties.

Synthesis and antimicrobial activity of a new series of 1,4-dihydropyridine derivatives

A series of 1,4-dihydropyridine derivatives (1a-g) were prepared from Hantzsch syntheses. The compounds 1a-g were reacted with thiosemicarbazide to give the new series of compounds 2a-g. IR, 1H-NMR, 13C-NMR, mass spectral and elemental analysis confirmed the synthesized compounds. The synthesized compounds were also screened for their antimicrobial activity.