127003-16-1

Basic information

• Product Name: <2-<2-<4-(4-carboxypiperidino)butoxy>phenyl>ethyl>benzene
• Synonyms: <2-<2-<4-(4-carboxypiperidino)butoxy>phenyl>ethyl>benzene
• CAS NO: 127003-16-1
• Molecular Weight: 381.515
• Mol File: 127003-16-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: <2-<2-<4-(4-carboxypiperidino)butoxy>phenyl>ethyl>benzene(CAS DataBase Reference)
• NIST Chemistry Reference: <2-<2-<4-(4-carboxypiperidino)butoxy>phenyl>ethyl>benzene(127003-16-1)
• EPA Substance Registry System: <2-<2-<4-(4-carboxypiperidino)butoxy>phenyl>ethyl>benzene(127003-16-1)

Safety Data

• Hazardous Substances Data: 127003-16-1(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 13246-50-9 benzylchlorotriphenylphosphorane 
• 18493-15-7 2-[(E/Z)-2-phenylvinyl]phenol 
• 7294-84-0 2-(2-phenylethyl)phenol 
• 498-94-2 isonipecotic acid 
• 72279-14-2 2-(4-bromobutoxy)-1-(2-phenylethyl)benzene 

Relevant articles and documents

Syntheses and Platelet Aggregation Inhibitory and Antithrombotic Properties of ethyl>benzenes

A series of ethyl>benzene derivatives were synthesized and evaluated for their ability to inhibit collagen-induced platelet aggregation in vitro and to protect experimantal thrombosis in mice.The results showed that the compounds were in vitro inhibitors of collagen-induced platelet aggregation.Most of them were also effective in the mouse antithrombotic assay.The compounds were found to be potent antagonists to S2 serotonergic receptor, and good correlation (r = 0.85) between their S2 serotonergic receptor antagonism and their potency as platelet antiaggregatory drugs was observed.Among the compounds studied, monophenoxy>methyl>ethyl>succinate hydrochloride (12b, MCI-9042) was selected for further pharmacological and toxicological evaluation.