1270083-83-4

Upstream product

• 4930-98-7 pyrid-2-ylhydrazine 
• 26510-95-2 ethyl 4-Bromobenzoylacetate 
• 1270084-03-1 3-(4-bromophenyl)-1-(pyridin-2-yl)-1H-pyrazol-5-yl acetate 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1270084-04-2 tert-butyl 1-(2-pyridinyl)-3-(4-biphenyl)-5-pyrazolyl carbonate 
• 1270084-06-4 tert-butyl 1-(2-pyridinyl)-3-[4-(3',4'-methylenedioxy)biphenyl]-5-pyrazolyl carbonate 
• 1270084-08-6 tert-butyl 1-(2-pyridinyl)-3-[4-(3'-phenyl)biphenyl]-5-pyrazolyl carbonate 
• 1270084-09-7 tert-butyl 1-(2-pyridinyl)-3-[4-(1-naphthyl)phenyl]-5-pyrazolyl carbonate 
• 1270084-11-1 tert-butyl 1-(2-pyridinyl)-3-[4-(3'-dimethylamino)biphenyl]-5-pyrazolyl carbonate 
• 1270084-49-5 1-(2-pyridinyl)-3-(4-biphenyl)-5-hydroxypyrazole 
• 1270084-50-8 1-(2-pyridinyl)-3-[4-(3',4'-methylenedioxy)biphenyl]-5-hydroxypyrazole 
• 1270084-52-0 1-(2-pyridinyl)-3-[4-(3'-phenyl)biphenyl]-5-hydroxypyrazole 
• 1270084-54-2 1-(2-pyridinyl)-3-[4-(1-naphthyl)phenyl]-5-hydroxypyrazole 
• 1270084-56-4 1-(2-pyridinyl)-3-[4-(3'-dimethylamino)biphenyl]-5-hydroxypyrazole 
• 1323987-86-5 C₂₃H₃₀BrN₃OSi 
• 1270083-94-7 3-(4-bromophenyl)-1-(pyridin-2-yl)-1H-pyrazol-5-yl t-butyl carbonate 
• 1270084-03-1 3-(4-bromophenyl)-1-(pyridin-2-yl)-1H-pyrazol-5-yl acetate 

Relevant academic research and scientific papers

COMPOSITION FOR PREVENTING OR TREATING KIDNEY DISEASE COMPRISING PYRAZOLE DERIVATIVE

The present invention provides a composition for preventing or treating kidney disease, the composition comprising a pyrazole derivative compound or a pharmaceutically acceptable salt thereof; and the composition of the present invention is effective in r

PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF, AND COMPOSITION FOR PREVENTION AND TREATMENT OF OSTEOPOROSIS CONTAINING SAME

The present invention provides pyrazole derivative compounds and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of preventing and treating osteoporosis.

Palladium-catalyzed peripheral arylation of 5-pyrazolones via enolizable bond protection

Peripheral cross-coupling of the enol form of the 5-pyrazolone scaffold with arylboronic acids promoted by [PdCldppf)] afforded the arylated products in good yields. In this coupling, the protection of the enolizable hydroxyl group of pyrazolone is a prer