127034-30-4

Basic information

• Product Name: 1-(2,5-dimethoxyphenyl)-3-[4-(diethylamino)phenyl]-2-methylprop-2-en-1-one
• CAS NO: 127034-30-4
• Molecular Weight: 353.461
• Mol File: 127034-30-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(2,5-dimethoxyphenyl)-3-[4-(diethylamino)phenyl]-2-methylprop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,5-dimethoxyphenyl)-3-[4-(diethylamino)phenyl]-2-methylprop-2-en-1-one(127034-30-4)
• EPA Substance Registry System: 1-(2,5-dimethoxyphenyl)-3-[4-(diethylamino)phenyl]-2-methylprop-2-en-1-one(127034-30-4)

Safety Data

• Hazardous Substances Data: 127034-30-4(Hazardous Substances Data)

Upstream product

• 5803-30-5 2',5'-dimethoxypropiophenone 
• 120-21-8 4-Diethylaminobenzaldehyde 

Relevant articles and documents

Novel use of compounds of the chalcones class

Process for inhibiting vascularization of a tumor mass comprising administering, in an amount effective to inhibit vascularization, at least one chalcone of formula (I): wherein: R is chosen from a hydrogen atom, a methyl group, an ethyl group, a chlorine atom, and a bromine atom, A is an NR1R2 group, wherein R1 and R2, which may be identical or different, are each chosen from a methyl group and an ethyl group, and n is an integer equal to 2 or 3.

Controlling the growth of certain tumor tissue with chalcone derivatives

Certain chalcone derivatives are reported to inhibit the polymerization of tubulin to form microtubules and are therefore antimitotic agents which can be used to control the growth of tumor tissue and can be used as antigout agents.