127040-01-1 Usage
Uses
Used in Pharmaceutical Industry:
Troglitazone glucuronide is used as a research compound for understanding the metabolism and elimination of troglitazone, which may have implications for the safety and efficacy of troglitazone therapy. The study of this metabolite can provide insights into the drug's pharmacokinetics and potential interactions with other medications or substances in the body.
Used in Toxicology Research:
Troglitazone glucuronide is used as a biomarker in toxicology research to investigate the liver toxicity associated with troglitazone. By analyzing the levels and elimination patterns of this metabolite, researchers can gain a better understanding of the drug's potential adverse effects and develop strategies to mitigate them.
Used in Drug Development:
Troglitazone glucuronide is used as a reference compound in the development of new drugs for the treatment of type 2 diabetes. By studying the properties and metabolism of this metabolite, researchers can design safer and more effective medications that avoid the liver toxicity issues associated with troglitazone.
Check Digit Verification of cas no
The CAS Registry Mumber 127040-01-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,0,4 and 0 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 127040-01:
(8*1)+(7*2)+(6*7)+(5*0)+(4*4)+(3*0)+(2*0)+(1*1)=81
81 % 10 = 1
So 127040-01-1 is a valid CAS Registry Number.
127040-01-1Relevant academic research and scientific papers
Studies on hindered phenols and analogues. V. Synthesis, identification and antidiabetic activity on the glucuronide of CS-045
Yoshioka,Aizawa,Fujita,Nakamura,Sasahara,Kuwano,Kinoshita,Horikoshi
, p. 2124 - 2125 (2007/10/02)
The glucuronide of a new oral antidiabetic agent, (±)-5-[4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl]thi azolidine-2,4-dione (CS-045) (1), was synthesized to confirm the structure of a metabolite in monkeys (Macaca fassicularis) and to exa
