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Cas No: 12705-41-8
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NotesPolymyxin B and colistimethate (cas 12705-41-8) are comparable as to efficacy and renal toxicity08/28/2019

We compared 41 patients who received colistimethate with 41 who received polymyxin B for the treatment of serious infections caused by carbapenem-resistant Acinetobacter spp. and found both polymyxins have similar efficacy and toxicity.detailed

Sodium colistimethate (cas 12705-41-8) loaded lipid nanocarriers for the treatment of Pseudomonas aeruginosa infections associated with cystic fibrosis08/27/2019

Lung impairment is the most life-threatening factor for cystic fibrosis patients. Indeed, Pseudomonas aeruginosa is the main pathogen in the pulmonary infection of these patients. In this work, we developed sodium colistimethate loaded lipid nanoparticles, namely, solid lipid nanoparticles (SLN)...detailed

Rapid communicationStability of colistimethate (cas 12705-41-8) sodium in a disposable elastomeric infusion device08/26/2019

Infections of the respiratory tract with Pseudomonas aeruginosa in cystic fibrosis patients are frequently treated with colistimethate sodium (CMS). For the intravenous administration of CMS a disposable elastomeric pump is a convenient option. To date, there are no data available on the chemica...detailed

Short communicationA simple method for assaying colistimethate (cas 12705-41-8) sodium in pharmaceutical aerosol samples using high performance liquid chromatography08/25/2019

A rapid and simple reversed-phase high performance liquid chromatography (HPLC) method for the quantitation of colistimethate sodium in pharmaceutical formulations has been developed. The chromatographic separation was performed using a Phenomenex Kinetex XB-C18 column with gradient elution usin...detailed

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