127055-11-2

Upstream product

• 127055-07-6 α-(Phenylthio)butanoyl chloride 
• 108908-63-0 N-4-methoxyphenyl-α-methylcinnamylideneamine 

Downstream Products

• 135616-78-3 (3S,4R)-3-[(S)-1-(Dimethyl-phenyl-silanyl)-ethyl]-1-(4-methoxy-phenyl)-4-((E)-1-methyl-2-phenyl-vinyl)-azetidin-2-one 
• 135616-78-3 (3S,4S)-3-[(S)-1-(Dimethyl-phenyl-silanyl)-ethyl]-1-(4-methoxy-phenyl)-4-((E)-1-methyl-2-phenyl-vinyl)-azetidin-2-one 
• 135616-77-2 3-Eth-(Z)-ylidene-1-(4-methoxy-phenyl)-4-((E)-1-methyl-2-phenyl-vinyl)-azetidin-2-one 
• 135616-76-1 3-Eth-(E)-ylidene-1-(4-methoxy-phenyl)-4-((E)-1-methyl-2-phenyl-vinyl)-azetidin-2-one 
• 135616-74-9 (S)-3-Benzenesulfinyl-3-ethyl-1-(4-methoxy-phenyl)-4-((E)-1-methyl-2-phenyl-vinyl)-azetidin-2-one 
• 118991-37-0 3-Ethyl-1-(4-methoxyphenyl)-4-(α-methylstyryl)azetidin-2-one 
• 118991-37-0 cis-3-ethyl-4-(α-methylstyryl)-1-(4-methoxyphenyl)azetidin-2-one 
• 118991-38-1 trans-3-ethyl-4-(α-methylstyryl)-1-(4-methoxyphenyl)azetidin-2-one 

Relevant academic research and scientific papers

Preparation of 3-Alkyl β-Lactams via the Ketene-Imine Cycloaddition Reaction Using α-(Phenylthio)alkanoyl Halides as Starting Materials:Application to the Synthesis of (+/-)-Carbapenem Building Blocks and Related Compounds

Preparation of appropriately substituted 3-alkyl β-lactams via the ketene (or equivalent)-imine cycloaddition reaction is described.The dehydrochlorination reaction of α-(phenylthio)alkanoyl chlorides with triethylamine in the presence of imines derived f

Alkyl(phenylthio)ketenes as Synthetic Equivalents of Monoalylketenes: A Concise General Route To 3-Alkyl β-Lactams as Carbapenem Building-Blocks

The dehydrochlorination of α-phenylthioalkanoyl chlorides with triethylamine in presence of imines produced a high yield formation of α-phenylthio β-lactams which upon desulfuration furnished a wide variety of 3-alkyl β-lactams in a high stereoselective f