127060-82-6

Basic information

• Product Name: (1R,3aR,6R,6aR)-(+)-6-(Benzoyloxy)-3,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-2(1H)-pentalenon
• Synonyms: (1R,3aR,6R,6aR)-(+)-6-(Benzoyloxy)-3,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-2(1H)-pentalenon
• CAS NO: 127060-82-6
• Molecular Weight: 286.371
• Mol File: 127060-82-6.mol

Chemical Properties

• CAS DataBase Reference: (1R,3aR,6R,6aR)-(+)-6-(Benzoyloxy)-3,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-2(1H)-pentalenon(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3aR,6R,6aR)-(+)-6-(Benzoyloxy)-3,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-2(1H)-pentalenon(127060-82-6)
• EPA Substance Registry System: (1R,3aR,6R,6aR)-(+)-6-(Benzoyloxy)-3,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-2(1H)-pentalenon(127060-82-6)

Safety Data

• Hazardous Substances Data: 127060-82-6(Hazardous Substances Data)

Upstream product

• 119433-11-3 (1R,2R,3R,5R,8R)-(+)-8-Benzoyloxy-2,7,7-trimethylbicyclo<3.3.0>octan-3-ol 
• 74552-31-1 (6R,7R)-(-)-7-Hydroxy-3-oxabicyclo<4.3.0>non-1-en-9-on 
• 119337-65-4 (1R,2S,6S)-2-Methyl-3-oxabicyclo<4.3.0>non-7-en-9-on 
• 119337-67-6 (1R,2S,6R,9R)-(-)-9-(tert-Butyldimethylsilyloxy)-2-methyl-3-oxabicyclo<4.3.0>nonan 
• 119337-70-1 tert-Butyl-dimethyl-((4aR,7R,7aS)-1-methyl-octahydro-cyclopenta[c]thiopyran-7-yloxy)-silane 
• 119337-72-3 (1R,2R,3R,5R,8R)-(-)-8-tert-Butyldimethylsilyloxy-2-methylbicyclo<3.3.0>octan-3-ol 
• 119337-74-5 (1R,3aR,5R,6R,6aR)-6-Methyl-5-(tetrahydro-pyran-2-yloxy)-octahydro-pentalen-1-ol 
• 119337-69-8 (1R,2R,3R,11'S)-(-)-1-(tert-Butyldimethylsilyloxy)-2-(1'-hydroxyethyl)-3-(2''-hydroxyethyl)cyclopentan 
• 119337-71-2 (3aR,6R,6aR)-(+)-6-(tert-Butyldimethylsilyloxy)-3,3a,4,5,6,6a-hexahydro-1-methylpentalen 
• 119337-68-7 (1R,2S,6R,9R)-(-)-9-(tert-Butyldimethylsilyloxy)-2-methyl-3-oxabicyclo<4.3.0>nonan-4-on 
• 119433-10-2 (3aR,5R,6R,6aR)-6-Methyl-5-(tetrahydro-pyran-2-yloxy)-hexahydro-pentalen-1-one 
• 119337-83-6 tert-Butyl-dimethyl-((4aR,7R,7aS)-1-methyl-2-oxo-octahydro-2λ⁴-cyclopenta[c]thiopyran-7-yloxy)-silane 
• 119337-73-4 tert-Butyl-dimethyl-[(1R,3aR,5R,6R,6aR)-6-methyl-5-(tetrahydro-pyran-2-yloxy)-octahydro-pentalen-1-yloxy]-silane 
• 119337-75-6 (3aR,5R,6R,6aR)-2,2,6-Trimethyl-5-(tetrahydro-pyran-2-yloxy)-hexahydro-pentalen-1-one 

Downstream Products

• 127060-83-7 (1S,3aR,6R,6aR)-(+)-6-(Benzoyloxy)-1-(2-chlor-2-propenyl)-3,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-2(1H)-pentalenon 
• 80677-96-9 (-)-Hypnophilin 
• 127001-14-3 (3aS,3bR,4R,6aS)-(-)-6-(Benzoyloxy)-3,3a,3b,4,5,6,6a,7-octahydro-3a,5,5-trimethyl-2H-cyclopentapentalen-2-on 
• 127060-84-8 (1S,3aR,6R,6aR)-(-)-6-Benzoyloxy-3,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-1-(2-oxopropyl)-2(1H)-pentalenon 
• 89002-35-7 4α-<(2-chloro-4-propylthio-1-buten)-3-yl>-6α-benzoyloxy-4β,7,7-trimethyl-1α,5α-bicyclo<3.3.0>-octan-3-one 
• 82873-81-2 (1SR,3aRS,6RS,6aRS)-6-benzoyloxy-1-(2-chloro-2-propenyl)-1,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-2(3H)-pentalenone 
• 82873-82-3 (1SR,3aRS,6RS,6aRS)-1-acetonyl-6-benzoyloxy-1,3a,4,5,6,6a-hexahydro-1,5,5-trimethyl-2(3H)-pentalenone 
• 85031-56-7 (3aR,3bS,4S,6aR,7R)-3,3a,5,5-Tetramethyl-3-phenylselanyl-4,7-bis-(tetrahydro-pyran-2-yloxy)-3,3a,3b,4,5,6,6a,7-octahydro-cyclopenta[a]pentalen-2-one 
• 82873-85-6 (3aR,3bS,4S,6aR,7R)-7-Hydroxy-3,3a,5,5-tetramethyl-3-phenylselanyl-4-(tetrahydro-pyran-2-yloxy)-3,3a,3b,4,5,6,6a,7-octahydro-cyclopenta[a]pentalen-2-one 

Relevant articles and documents

Chemistry and Stereochemistry of Iridoids, XVI. - EPC-Synthesis of (-)-Hypnophilin

The synthesis of enantiomerically pure (-)-hypnophilin (27) from (6R,7R)-(-)-7-hydroxy-3-oxabicyclonon-1-en-9-one (1) is described. 1 was obtained in 93 percent yield from catalpol, which is readily available from the aqueous sodium carbonate extra

THE SYNTHESIS OF dl-CORIOLIN

The synthesis of dienone 2, which has previously been converted into the title compound in one step, is described.The methanoindene 7 is transformed into dienone-alcohol 58 in eighteen steps (12percent overall yield).This was then hydroxylated at C-8, usi

SYNTHESIS OF dl-CORIOLIN

The total synthesis of dl-coriolin has been achieved in a stereoselective way.The key tricyclic intermediate was synthesized from dicyclopentadiene through a route which involved an SN2 reaction at a neopentylic position.

THE SYNTHESIS OF d,l-CORIOLIN

The formal synthesis of coriolin (1) from methanoindene 2 is described.

A NEW SYNTHESIS OF dl-CORIOLIN A. APPLICATION OF A NEW SN2 REACTION AT A NEOPENTYLIC POSITION

Dicyclopentadiene has been stereoselectively converted to a key tricyclic intermediate for the total synthesis of coriolin, through a route which involves a new SN2 reaction at a neopentylic position.