127082-54-6Relevant articles and documents
[Cp*RhIII]/Ionic Liquid as a Highly Efficient and Recyclable Catalytic Medium for C?H Amidation
Ma, Qiang,Yu, Xinling,Lai, Ruizhi,Lv, Songyang,Dai, Weiyang,Zhang, Chen,Wang, Xiaolong,Wang, Qiantao,Wu, Yong
, p. 3672 - 3678 (2018/09/29)
A [Cp*RhIII]-catalyzed direct C?H amidation is carried out in ionic liquid. Both C(sp2)?H bonds of (hetero)arenes and alkenes and unactivated C(sp3)?H bonds can be easily amidated with high functional-group tolerance and excellent yields under these conditions. Notably, using [Cp*RhIII]/[BMIM]BF4 (BMIM=1-butyl-3-methylimidazolium) as the green and recyclable medium is environmentally benign, in light of characteristics such as the reusability of the expensive rhodium catalyst, avoidance of highly toxic organic solvents, and mild reaction conditions, as well as a short reaction time.
Mechanism of alkaline cyclization of 2-(substituted benzamido)benzamides to 4-quinazolinones
Gardner,Kanagasooriam,Smyth,Williams
, p. 6245 - 6250 (2007/10/02)
The title amides cyclize rapidly to the corresponding quinazolin-4-ones in aqueous alkaline solution at 25°C; the pseudo-first-order rate constants fit the empirical equation k(obs) = k(max) [OH-]/(K(m) + [OH-] + [OH-]sup
