127104-26-1

Basic information

• Product Name: N-(1-PYRIDIN-2-YL-ETHYL)-HYDROXYLAMINE
• Synonyms: 2-Pyridinemethanamine,N-hydroxy-alpha-methyl-(9CI);N-(1-PYRIDIN-2-YL-ETHYL)-HYDROXYLAMINE
• CAS NO: 127104-26-1
• Molecular Formula: C₇H₁₀N₂O
• Molecular Weight: 138.17
• Product Categories: PYRIDINE
• Mol File: 127104-26-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 266.3°Cat760mmHg
• Flash Point: 114.8°C
• Appearance: /
• Density: 1.127g/cm³
• Vapor Pressure: 0.00435mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: N-(1-PYRIDIN-2-YL-ETHYL)-HYDROXYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-PYRIDIN-2-YL-ETHYL)-HYDROXYLAMINE(127104-26-1)
• EPA Substance Registry System: N-(1-PYRIDIN-2-YL-ETHYL)-HYDROXYLAMINE(127104-26-1)

Safety Data

• Hazardous Substances Data: 127104-26-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H10N2O/c1-6(9-10)7-4-2-3-5-8-7/h2-6,9-10H,1H3

Upstream product

• 1122-62-9 2-acetylpyridine 
• 1758-54-9 1-pyridin-2-yl-ethanone oxime 

Downstream Products

• 127104-42-1 (R*,S*)-N-hydroxy-N-<1-(1-pyridyl)ethyl>-1-phenylethanamine 
• 127104-42-1 (R*,R*)-N-hydroxy-N-<1-(1-pyridyl)ethyl>-1-phenylethanamine 
• 127104-30-7 N-benzylidene-1-(2-pyridyl)ethanamine N-oxide 

Relevant articles and documents

Diastereoselectivity of Organometallic Additions to Nitrones Bearing Sterogenic N-Substituents

The diastereoselectivity of organometallic additions to nitrones bearing stereogenic α-arylethyl, β-methoxyalkyl, and β-(silyloxy)alkyl substituents on nitrogen has been investigated.High and complementary diastereoselectivity (90-94percent) was observed in the additions of Grignard reagents to nitrones (e.g. 22 and 23) bearing the potentially chelating β-methoxyalkyl group.However, the opposite selectivity resulted from the reaction of methylmagnesium bromide with the corresponding silyl ether (27).The relative stereochemistry of selected hydroxylamine adducts wasestablished by reduction of their phosphate and carbonate derivatives to known amines (37a,b and 39), by periodate cleavage of a β-hydroxy hydroxylamine (41b), and by various correlations (Scheme II).The high facial diastereoselectivity observed with the N-(β-methoxyalkyl)nitrones is explained by a simple chelation model (Scheme III).