127117-45-7

Basic information

• Product Name: 2-Azabicyclo[3.1.0]hexane-1-carboxamide,2-acetyl-N-methyl-(9CI)
• Synonyms: 2-Azabicyclo[3.1.0]hexane-1-carboxamide,2-acetyl-N-methyl-(9CI)
• CAS NO: 127117-45-7
• Molecular Formula: C9H14N2O2
• Molecular Weight: 182.21966
• Product Categories: PYRROLE
• Mol File: 127117-45-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Azabicyclo[3.1.0]hexane-1-carboxamide,2-acetyl-N-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azabicyclo[3.1.0]hexane-1-carboxamide,2-acetyl-N-methyl-(9CI)(127117-45-7)
• EPA Substance Registry System: 2-Azabicyclo[3.1.0]hexane-1-carboxamide,2-acetyl-N-methyl-(9CI)(127117-45-7)

Safety Data

• Hazardous Substances Data: 127117-45-7(Hazardous Substances Data)

Usage

Class of Compound

Cycloalkanecarboxamides

Parent Compound

Bicyclic amine 2-azabicyclo[3.1.0]hexane

Functional Groups

Carboxamide group
Acetyl group

Substituents

Methyl group on the nitrogen atom of the carboxamide group

Biological Activity

Potential pharmaceutical applications, particularly in the nervous system

Research Status

Further research and testing required to fully understand properties and potential uses

Upstream product

• 127117-43-5 N-benzyloxycarbonyl-2,3-methanoproline-O-tBu 
• 74409-25-9 1-Pyrrolin-2-carbonsaeure-tert-butylester 
• 75176-38-4 1-Benzyloxycarbonyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid,tert-butyl ester 
• 127117-44-6 2,3-methanoproline-O-tBu 
• 593-51-1 methylamine hydrochloride 
• 127117-46-8 N-acetyl-2,3-methanoproline-O-tBu 

Relevant articles and documents

Synthesis of (+/-)-2,3-Methanoproline: A Novel Inhibitor of Ethylene Biosynthesis

The title compound, 2-aza-bicyclohexane-1-carboxylic acid (2) was prepared by treatment of N-benzyloxycarbonyl-2,3-dehydroproline tert-butyl ester with diazomethane followed by photolysis of the resulting pyrazoline and deprotection.Its N-acetyl-N'-methyl amide, a peptide mimic, was synthesized and the structure of was confirmed by X-ray diffraction studies.NMR spectroscopy was also used to examine the effect of the cyclopropane ring on its conformation.This 2,3-methanoamino acid (2) was found to be a weak inhibitor of ethylene biosynthesis in cucumber cotyledon strips and germinating squash seeds.The data show that 2 probably inhibits the conversion of 1-aminocyclopropanecarboxylic acid to ethylene in these tissues.