127128-05-6 Usage
Chemical origin
Derived from the omega-3 fatty acid eicosapentaenoic acid (EPA)
Production
Enzyme-catalyzed reaction between EPA and glutathione, a major antioxidant in cells
Anti-inflammatory properties
Demonstrated potent anti-inflammatory effects
Cytoprotective properties
Exhibits cytoprotective properties
Physiological processes
Implicated in immune function, vascular tone regulation, and tissue repair
Role in inflammation resolution
Plays a role in the resolution of inflammation
Modulation of oxidative stress
Involved in the modulation of oxidative stress
Therapeutic potential
Being studied for potential therapeutic applications in various diseases
Disease focus
Particularly relevant to diseases characterized by chronic inflammation and oxidative damage
This list provides a concise overview of the key properties and content related to 11-glutathionylhepoxilin A3, as described in the provided material.
Check Digit Verification of cas no
The CAS Registry Mumber 127128-05-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,1,2 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 127128-05:
(8*1)+(7*2)+(6*7)+(5*1)+(4*2)+(3*8)+(2*0)+(1*5)=106
106 % 10 = 6
So 127128-05-6 is a valid CAS Registry Number.
InChI:InChI=1/C30H49N3O10S/c1-2-3-4-5-6-10-13-24(35)25(17-15-21(34)12-9-7-8-11-14-26(36)37)44-20-23(30(43)32-19-28(40)41)33-29(42)22(31)16-18-27(38)39/h6-7,9-10,15,17,21-25,34-35H,2-5,8,11-14,16,18-20,31H2,1H3,(H,32,43)(H,33,42)(H,36,37)(H,38,39)(H,40,41)/b9-7+,10-6+,17-15+/t21?,22-,23-,24?,25?/m0/s1
127128-05-6Relevant articles and documents
(8-R)- and (8-S)-hepoxilin A3. Assignment of configuration and conversion to biologically active conjugates with glutatione
Corey,Su
, p. 2113 - 2116 (2007/10/02)
The determination of absolute configuration of (8-R)-hepoxilin A3 (2) (more polar methyl ester) and (8-S)-hepoxilin A3 (3) (less polar methyl ester) is reported along with the synthesis of the biologically active 11-R glutathione thiol conjugates 4 and 5 which may function as important neuromodulators.
