1271318-61-6 Usage
Description
PETROMYZONOL-24-SULFATE, SODIUM SALT, also known as Petromyzonol sulfate (PZS), is a bile salt derivative that is isolated from the sea lamprey (Petromyzon marinus) ammocoete, which is the larval form of the sea lamprey. It is characterized by its off-white solid appearance and is known to function as a spawning chemoattractant for the sea lamprey.
Uses
Used in Marine Biology and Ecology:
PETROMYZONOL-24-SULFATE, SODIUM SALT is used as a chemoattractant for the sea lamprey, specifically to stimulate spawning behavior in this species. This application is crucial for the study and conservation of the sea lamprey population, as it helps researchers understand and monitor their reproductive patterns and overall health.
Used in Pharmaceutical Research:
PETROMYZONOL-24-SULFATE, SODIUM SALT is used as a research compound for investigating its potential applications in the pharmaceutical industry. Given its unique chemical properties and biological activity as a chemoattractant, it may hold promise for the development of new drugs or therapies targeting various medical conditions.
Used in Chemical Synthesis:
As an off-white solid with distinct chemical properties, PETROMYZONOL-24-SULFATE, SODIUM SALT can be used as a starting material or intermediate in the synthesis of other related compounds. This application is particularly relevant in the field of organic chemistry, where it may contribute to the development of novel molecules with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1271318-61-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,1,3,1 and 8 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1271318-61:
(9*1)+(8*2)+(7*7)+(6*1)+(5*3)+(4*1)+(3*8)+(2*6)+(1*1)=136
136 % 10 = 6
So 1271318-61-6 is a valid CAS Registry Number.
1271318-61-6Relevant articles and documents
Synthesis and olfactory activity of unnatural, sulfated 5β-bile acid derivatives in the sea lamprey (Petromyzon marinus)
Burns, Aaron C.,Sorensen, Peter W.,Hoye, Thomas R.
, p. 291 - 300 (2011/03/21)
A variety of unnatural bile acid derivatives (9a-9f) was synthesized and used to examine the specificity with which the sea lamprey (Petromyzon marinus) olfactory system detects these compounds. These compounds are analogs of petromyzonol sulfate (PS, 1), a component of the sea lamprey migratory pheromone. Both the stereochemical configuration at C5 (i.e., 5α vs. 5β) and the extent and sites of oxygenation (hydroxylation or ketonization) of the bile acid derived steroid skeleton were evaluated by screening the compounds for olfactory activity using electro-olfactogram recording. 5β-Petromyzonol sulfate (9a) elicited a considerable olfactory response at sub-nanomolar concentration. In addition, less oxygenated systems (i.e., 9b-9e) elicited olfactory responses, albeit with less potency. The sea lamprey sex pheromone mimic 9f (5β-3-ketopetromyzonol sulfate) was also examined and found to produce a much lower olfactory response. Mixture studies conducted with 9a and PS (1) suggest that stimulation is occurring via similar modes of activation, demonstrating a relative lack of specificity for recognition of the allo-configuration (i.e., 5α) in sea lamprey olfaction. This attribute could facilitate design of pheromone analogs to control this invasive species.
