127132-38-1

Basic information

• Product Name: BOC-L-TYR(ALL)-OH
• Synonyms: N-ALPHA-TERT-BUTYLOXYCARBONYL-O-ALLYL-L-TYROSINE;N-ALPHA-T-BUTYLOXYCARBONYL-O-ALLYL-L-TYROSINE;BOC-TYR(ALL)-OH;BOC-TYR(ALLYL)-OH;BOC-TYR(AL)-OH;BOC-L-TYR(ALL)-OH;BOC-L-TYROSINE ALLYL ESTER;BOC-O-ALLYL-L-TYROSINE
• CAS NO: 127132-38-1
• Molecular Formula: C₁₇H₂₃NO₅
• Molecular Weight: 321.37
• Mol File: 127132-38-1.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 490.39 °C at 760 mmHg
• Flash Point: 250.379 °C
• Appearance: /
• Density: 1.145 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.526
• Storage Temp.: 2-8°C
• BRN: 3624582
• CAS DataBase Reference: BOC-L-TYR(ALL)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-L-TYR(ALL)-OH(127132-38-1)
• EPA Substance Registry System: BOC-L-TYR(ALL)-OH(127132-38-1)

Safety Data

• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 127132-38-1(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

Uses

Due to gem-dimethyl substituent effect, Boc-Tyr(Allyl)-OH is found to be resistant to Claisen rearrangement in water.

InChI:InChI=1/C17H23NO5/c1-5-10-22-13-8-6-12(7-9-13)11-14(15(19)20)18-16(21)23-17(2,3)4/h5-9,14H,1,10-11H2,2-4H3,(H,18,21)(H,19,20)/t14-/m0/s1

Upstream product

• 147363-23-3 methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[4-(prop-2-en-1-yloxy)phenyl]-propanoate 
• 4326-36-7 (S)-N-(tert-butoxycarbonyl)tyrosine methyl ester 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 18938-60-8 (S)-tert-butyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanoate 
• 72594-77-5 N-(tert-butoxycarbonyl)-L-tyrosine ethyl ester 
• 949-67-7 L-tyrosine ethyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 3978-80-1 Boc-Tyr-OH 
• 156945-63-0 (S)-3-(4-Allyloxy-phenyl)-2-tert-butoxycarbonylamino-propionic acid allyl ester 
• 106-95-6 allyl bromide 
• 127132-37-0 (S)-Ethyl 3-(4-(allyloxy)phenyl)-2-((tert-butoxycarbonyl)amino) propanoate 

Downstream Products

• 127132-40-5 N-(tert-butoxycarbonyl)-L-valyl-O'-(prop-2-enyl)-L-tyrosyl-L-valine methyl ester 
• 127132-39-2 O'-(prop-2-enyl)-L-tyrosyl-L-valine methyl ester hydrochloride 
• 127132-42-7 N-(trifluoroacetyl)-L-valyl-O'-(prop-2-enyl)-L-tyrosyl-L-valine methyl ester 
• 127132-43-8 N-(trifluoroacetyl)-L-valyl-O'-(2,3-epoxypropyl)-L-tyrosyl-L-valine methyl ester 
• 127132-41-6 L-valyl-O'-(prop-2-enyl)-L-tyrosyl-L-valine methyl ester hydrochloride 
• 1028203-38-4 3-(4-allyloxy-phenyl)-(2S)-2-tert-butoxycarbonylamino-propionic acid dec-9-enyl ester 
• 1028203-37-3 3-(4-allyloxy-phenyl)-(2S)-2-tert-butoxycarbonylamino-propionic acid but-3-enyl ester 
• 169157-95-3 {4-[3-(4-allyloxy-phenyl)-2-amino-propionyl]-3-methoxycarbonylmethyl-2-oxo-piperazin-1-yl}-acetic acid 
• 177842-05-6 (S)-3-(4-Allyloxy-phenyl)-2-amino-propionic acid; hydrochloride 
• 3978-80-1 Boc-Tyr-OH 

Relevant articles and documents

Divergent and site-selective solid-phase synthesis of sulfopeptides

On solid ground: A solid-phase strategy for the efficient synthesis of sulfopeptides is described. Selective deprotection of orthogonally-protected tyrosine residues and solid-phase sulfation provided divergent access to differentially sulfated peptides in high yields. Copyright

Chiral Lewis acids supported on silica gel and alumina, and their use as catalysts in Diels-Alder reactions of methacrolein and bromoacrolein

Several derivatives of (S)-tyrosine are supported on silica gel through the phenolic oxygen atom. The Lewis acids obtained by treatment of these solids with BH3 are able to promote the reactions of methacrolein and bromoacrolein with cyclopenta

Design and synthesis of β-strand-fixed peptides inhibiting aggregation of amyloid β-protein

Aggregation of 42-residue amyloid β-protein (Aβ42) can be prevented by β-sheet breaker peptides (BSBps) homologous to LVFFA residues, which are included in a β-sheet region of Aβ42 aggregates. To enhance the affinity of BSBps to the Aβ42 aggregates, we de

The selective incorporation of alkenes into proteins in Escherichia coli.

-