127156-29-0

Basic information

• Product Name: 9α-hydroxy-2β-methoxyclovane
• CAS NO: 127156-29-0
• Molecular Weight: 252.397
• Mol File: 127156-29-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9α-hydroxy-2β-methoxyclovane(CAS DataBase Reference)
• NIST Chemistry Reference: 9α-hydroxy-2β-methoxyclovane(127156-29-0)
• EPA Substance Registry System: 9α-hydroxy-2β-methoxyclovane(127156-29-0)

Safety Data

• Hazardous Substances Data: 127156-29-0(Hazardous Substances Data)

Upstream product

• 60594-23-2 4α,5α-epoxyisocaryophyllene 

Relevant articles and documents

REARRANGED CARYOPHYLLENES BY BIOTRANSFORMATION WITH CHAETOMIUM COCHLIODES

Biotransformation of caryophyllene by Chaetomium cochliodes DSM 1909 (=ATCC 10195) leads to 4,5-epoxy-caryophyllene-7,12-diol as the main product.The hydroxylation of the geminal methyl groups is not very stereospecific, but as with Diploida gossypina the main product possesses the 11R-configuration.Side-reactions are ring contraction or formation of clovanes, probably via epoxide rearrangements.The use of mono- or diepoxy-caryophyllene as the substrate does not increase the yields significantly.Instead, diepoxy-caryophyllene gave a punctatin derivative.The same molecular framework, but with a different configuration, was observed among the fermentation products from Diplodia gossypina, which supports the assumption that a caryophyllane is the precursor of this class of antibiotics.