127236-29-7Relevant academic research and scientific papers
An efficient, one-pot synthesis of 1,3-thiazines and 1,2,3,5-thiatriazines from N-(trimethylsilyl)imines via [4 + 2] cycloaddition of 1-thia-3-azadienes
Barluenga,Tomas,Ballesteros,Lopez
, p. 985 - 988 (1995)
The [4 + 2] cycloaddition reaction of 2-amino-1-thia-3-azabutadienes 2, formed in situ from N-(trimethylsilyl)imines 1 and phenyl isothiocyanate, towards electron-poor dienophiles is described. The process is applied to a number of carbo- and heterodienophiles, allowing the regioselective formation of the cycloadducts 3-7 with complete endo-stereoselectivity.
CYCLOADDITION REACTIONS OF HETEROAZADIENES: CYCLOADDITION OF 1-THIA-3-AZABUTADIENES WITH ELECTRON-POOR DIENOPHILES.
Barluenga, Jose,Tomas, Miguel,Ballesteros, Alfredo,Lopez, Luis A.
, p. 6923 - 6926 (2007/10/02)
1-Thia-3-azabutadienes cleanly undergo cycloaddition processes with electron-poor dienophiles; the reaction is regioselective and leads exclusively to the endo isomer.
