127244-92-2

Upstream product

• 83629-88-3 4-bromo-5-(p-tolyl)-2,3-dihydro-2,3-furandione 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 127244-96-6 [4-Bromo-2-hydroxy-1-(4-methoxy-phenyl)-3-oxo-5-p-tolyl-2,3-dihydro-1H-pyrrol-2-yl]-acetic acid methyl ester 
• 140628-30-4 [1-(2-Amino-5-nitro-phenyl)-4-bromo-2-hydroxy-3-oxo-5-p-tolyl-2,3-dihydro-1H-pyrrol-2-yl]-acetic acid methyl ester 
• 140628-28-0 [1-(2-Amino-phenyl)-4-bromo-2-hydroxy-3-oxo-5-p-tolyl-2,3-dihydro-1H-pyrrol-2-yl]-acetic acid methyl ester 
• 140628-35-9 3-(4-Bromo-3-oxo-5-p-tolyl-2,3-dihydro-furan-2-yl)-3,4-dihydro-1H-quinoxalin-2-one 
• 127244-99-9 Bromo-(2,4-dibromo-3-oxo-5-p-tolyl-2,3-dihydro-furan-2-yl)-acetic acid methyl ester 

Relevant academic research and scientific papers

CHEMISTRY OF 2-METHYLENE-2,3-DIHYDROFURAN-3-ONES. 2. 2-ALKOXYCARBONYLMETHYLENE-5-ARYL-4-HALO-2,3-DIHYDROFURAN-3-ONES: SYNTHESIS, STRUCTURE, AND PROPERTIES

Reaction of 5-aryl-4-halo-2,3-dihydrofuran-2,3-diones with alkoxycarbonylmethylenetriphenylphosphoranes has given 2-alkoxycarbonylmethylene-5-aryl-4-halo-2,3-dihydrofuran-3-ones, which readily add halogens at the 2-exocyclic double bond, and on reaction with arylamines recyclize to give 2-hydroxy-2,3-dihydropyrrol-3-ones.