127253-94-5

Upstream product

• 941-69-5 N-phenyl-maleimide 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 127196-21-8 (R)-(-)-methyl 4-phenyl-3-oxazolidineacetate 

Downstream Products

• 150180-20-4 2-((R)-2-Hydroxy-1-phenyl-ethyl)-4,6-dioxo-5-phenyl-octahydro-pyrrolo[3,4-c]pyrrole-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

High diastereofacial selectivity in the 1,3-dipolar cycloaddition of chiral azomethine ylides

Excellent diastereofacial and endo/exo stereoselectivities have been obtained in cycloaddition of the chiral azomethine ylide generated from 4-phenyloxazolidine acetic acid (-)-8-phenylmenthyl ester 1e.

Asymmetric Synthesis XVII : Facile Generation of a Chiral Azomethine Ylide via the CN(R,S) Method

(-)-N-cyanomethyl-4-phenyl-1,3-oxazolidine, prepared in one step from R-(-)-phenylglycinol, gives a chiral azomethine ylide on treatment with TMSOTf and (iPr)2NEt.This ylide undergoes 1,3-dipolar cycloaddition reactions with activated olefins under very m