1272671-89-2Relevant academic research and scientific papers
Highly regioselective cyclotrimerization of terminal alkynes catalyzed by Fe(II) complexes bearing 2-(benzimidazolyl)-6-(1-(arylimino)ethyl)pyridines
Liu, Yongbing,Yan, Xiaoyu,Yang, Nianfa,Xi, Chanjuan
, p. 489 - 492 (2011)
FeCl2 ligated with 2-(benzimidazolyl)-6-(1-(arylimino)ethyl) pyridine in the presence of zinc powder and zinc iodide could effectively catalyze cyclotrimerization of intermolecular alkynes to afford benzene derivatives in high regioselectivity. The synthetic usefulness of this catalytic system consisting of Fe(II) complex C1, Zn and ZnI2 in acetonitrile was tested with various terminal alkynes. In the cases of using aryl substituted alkynes, the 1,2,4-trisubstituted benzenes 2 were found to be the major products.
Exploiting guanidine as a ligand in cobalt-catalyzed alkyne cyclotrimerizations
Eichman, Chad C.,Bragdon, Jason P.,Stambuli, James P.
supporting information; experimental part, p. 1109 - 1112 (2011/06/20)
The synthesis of polysubstituted arenes is accomplished via the regioselective cyclotrimerization of alkynes utilizing a guanidine-ligated cobalt catalyst. Georg Thieme Verlag Stuttgart - New York.
