1272675-76-9Relevant academic research and scientific papers
Synthesis of 6,14-epoxymorphinan derivatives and their pharmacologies
Nemoto, Toru,Yamamoto, Naoshi,Watanabe, Akio,Fujii, Hideaki,Hasebe, Ko,Nakajima, Mayumi,Mochizuki, Hidenori,Nagase, Hiroshi
, p. 1205 - 1221 (2011/04/12)
A novel 6,14-epoxymorphinan benzamide derivative (NS22) that was previously reported showed opioid κ receptor agonistic activity and analgesic activity. The unsatisfactory κ selectivity of NS22 led us to synthesize its derivatives to improve the opioid κ
