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1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE, also known as DiD, is a lipophilic fluorescent probe that is rapidly incorporated into phospholipid cell membranes. It has been used to label the plasma membrane and endocytic organelles in various cell types, including bovine aorta endothelial cells and rat hippocampal slices. DiD is not cytotoxic and can be detected in vivo after three weeks. It displays absorption/emission maxima of 650/670 nm, respectively.

127274-91-3

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127274-91-3 Usage

Uses

Used in Cell Biology Research:
DiD is used as a fluorescent probe for cell biology research to label the plasma membrane and endocytic organelles, allowing for the visualization and study of cellular processes.
Used in Cancer Research:
DiD is used as a proliferation marker in cancer research, particularly in prostate cancer cell lines. High DiD-expressing cell populations are associated with lower proliferation, making it a useful tool for assessing cancer cell growth and behavior.
Used in In Vivo Imaging:
DiD is used for in vivo imaging, as it can be detected in subcutaneously implanted PC3 cells after three weeks. This allows for the monitoring of tumor growth and the evaluation of therapeutic interventions in animal models.
Used in Drug Delivery Systems:
Although not explicitly mentioned in the provided materials, DiD's lipophilic nature and ability to be incorporated into cell membranes suggest that it could potentially be used in drug delivery systems to improve the targeting and efficacy of therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 127274-91-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,2,7 and 4 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 127274-91:
(8*1)+(7*2)+(6*7)+(5*2)+(4*7)+(3*4)+(2*9)+(1*1)=133
133 % 10 = 3
So 127274-91-3 is a valid CAS Registry Number.

127274-91-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE

1.2 Other means of identification

Product number -
Other names 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindodicarbovyanineperchlorate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127274-91-3 SDS

127274-91-3Upstream product

127274-91-3Downstream Products

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