1272754-98-9Relevant articles and documents
ONE-BEAD-TWO-COMPOUND MACROCYCLIC LIBRARY AND METHODS OF PREPARATION AND USE
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Paragraph 0160; 0161; 0169, (2018/11/02)
A one-bead-two-compound combinatorial synthesis technique provides libraries of macrocyclic peptidomimetic compounds and compositions with use as ligands for the Ephrin type-A receptor 2 (EphA2). The one-bead-two-compound technique and libraries of macrocyclic compounds are useful as research tools in drug discovery and/or to treat or prevent a range of diseases or disorders.
Synthesis and applications of polyamine amino acid residues: Improving the bioactivity of an analgesic neuropeptide, neurotensin
Zhang, Liuyin,Lee, Hee-Kyoung,Pruess, Timothy H.,White, H. Steve,Bulaj, Grzegorz
supporting information; experimental part, p. 1514 - 1517 (2010/02/28)
Conjugated polyamines are potential carriers for biothera- peutics targeting the central nervous system. We describe an efficient synthesis of a polyamine-based amino acid, lysine-trimethylene(diNo-syl)-spermine(triBoc) with Dde or Fmoc orthogonal protect