127292-12-0Relevant articles and documents
Synthesis of α-amino acid amides: Ruthenium-catalyzed amination of α-hydroxy amides
Zhang, Min,Imm, Sebastian,Baehn, Sebastian,Neumann, Helfried,Beller, Matthias
supporting information; experimental part, p. 11197 - 11201 (2012/02/03)
Give me an N: The catalytic amination of α-hydroxy amides with a variety of amines, including anilines, primary and secondary aliphatic amines, and ammonia, yields a wide range of α-amino amides (see scheme). This atom-efficient amination protocol proceeds efficiently in the presence of a commercially available [Ru3(CO)12]/DCPE catalyst system. Copyright