127292-60-8

Basic information

• Product Name: [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl-
• Synonyms: [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl-;N,N-dimethyl-[1,1'-Biphenyl]-4-methanamine
• CAS NO: 127292-60-8
• Molecular Formula: C₁₅H₁₇N
• Molecular Weight: 211.30218
• Mol File: 127292-60-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 112-114 °C(Press: 0.02 Torr)
• Appearance: /
• Density: 1.000±0.06 g/cm3(Predicted)
• PKA: 8.69±0.28(Predicted)
• CAS DataBase Reference: [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl-(127292-60-8)
• EPA Substance Registry System: [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl-(127292-60-8)

Safety Data

• Hazardous Substances Data: 127292-60-8(Hazardous Substances Data)

Usage

General Description

[1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl- is a chemical compound with the molecular formula C15H15N. It is commonly referred to as 4,4'-Dimethylaminobiphenyl and is used as a building block in the synthesis of various pharmaceuticals and organic compounds. It is a tertiary amine, meaning it contains three methyl groups attached to the nitrogen atom, which gives it unique properties and reactivity. [1,1'-Biphenyl]-4-MethanaMine, N,N-diMethyl- is often used as a catalyst in organic reactions and as a precursor for the synthesis of dyes, pigments, and optical brighteners. Its versatile nature makes it an important intermediate in the field of organic chemistry.

Upstream product

• 33322-67-7 N, N-dimethyl [1,1’-biphenyl]-4-carboxamide 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 15184-98-2 N,N-dimethyl-4-chlorobenzylamine 
• 98-80-6 phenylboronic acid 
• 2567-29-5 p-phenylbenzyl bromide 
• 506-59-2 N,N-dimethylammonium chloride 
• 3218-36-8 4-Phenylbenzaldehyde 
• 124-40-3 dimethyl amine 
• 6274-57-3 (4-bromobenzyl)dimethylamine 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 644-08-6 4-Methylbiphenyl 
• 3597-91-9 biphenyl-4-yl methanol 

Downstream Products

• 67362-98-5 2-([1,1′-biphenyl]-4-yl)benzo[d]thiazole 
• 5728-52-9 (4-biphenylyl)acetic acid 
• 27643-99-8 2-([1,1'-biphenyl]-4-yl)-1-phenylethan-1-ol 
• 644-08-6 4-Methylbiphenyl 
• 3218-36-8 4-Phenylbenzaldehyde 

Relevant articles and documents

Ambidextrous 'hybrid' fluorinated zwitterionic geminis: self-assembly in both organic and aqueous media

-

Controlled Reduction of Carboxamides to Alcohols or Amines by Zinc Hydrides

New protocols for controlled reduction of carboxamides to either alcohols or amines were established using a combination of sodium hydride (NaH) and zinc halides (ZnX2). Use of a different halide on ZnX2 dictates the selectivity, wherein the NaH-ZnI2 system delivers alcohols and NaH-ZnCl2 gives amines. Extensive mechanistic studies by experimental and theoretical approaches imply that polymeric zinc hydride (ZnH2)∞ is responsible for alcohol formation, whereas dimeric zinc chloride hydride (H?Zn?Cl)2 is the key species for the production of amines.

METHODS FOR EXTERNAL BASE-FREE SUZUKI COUPLINGS

The present disclosure describes a method of coupling a first aromatic compound to a second aromatic compound, the method comprising: (a) preparing a reaction mixture comprising the first aromatic compound, the second aromatic compound, a catalyst and water; the reaction mixture does not contain an external base, the reaction mixture having an initial pH of from 11 to 1; the catalyst having at least one group 10 atom; the first aromatic compound having a halogen, triflate or sulfonate substituent; the second aromatic compound having a boron-containing substituent; wherein, at least one of the first aromatic compound or the second aromatic compound includes one or more heteroatom; and (b) reacting the first aromatic compound and the second aromatic compound in the reaction mixture, the reaction mixture having a final pH following reaction of the first aromatic compound and the second aromatic compound.