127322-76-3Relevant academic research and scientific papers
Visible-light-induced aerobic epoxidation in cyclic ether: Synthesis of spiroepoxyoxindole derivatives
Luo, Kaixiu,Yu, Xianglin,Chen, Peng,He, Kun,Lin, Jun,Jin, Yi
, (2020)
A visible-light-induced aerobic epoxidation of 3-benzylideneindolin-2-ones with a meso-Tetraphenylporphyrin (TPP) photosensitizer in cyclic ether has been established for the efficient synthesis of spiroepoxyoxindole derivatives. This reaction leads to ex
Structure Elucidation of the First Inhibitors of Human Papillomavirus Type 11 E1-E2 Protein-Protein Interaction
Yoakim, Christiane,Goudreau, Nathalie,McGibbon, Graham A.,O'Meara, Jeff,White, Peter W.,Ogilvie, William W.
, p. 3427 - 3444 (2003)
A novel series of inhibitors of the HPV11 E1-E2 protein-protein interaction was identified. These inhibitors, which were discovered as a result of high-throughput screening, feature an indandione system spirofused onto an appropriately substituted tetrahy
A series of spirocyclic analogues as potent inhibitors of bacterial phenylalanyl-tRNA synthetases
Yu, Xiang Y.,Finn, John,Hill, Jason M.,Wang, Zhong G.,Keith, Dennis,Silverman, Jared,Oliver
, p. 1339 - 1342 (2007/10/03)
We have identified a series of spirocyclic furan and pyrrolidine inhibitors of Enterococeus faecalis and Staphylococcus aureus phenylalanyl-tRNA synthetases. The most potent analogue 1b showed IC50=5 nM (E. faecalis PheRS) and IC50=2
Discovery of the first series of inhibitors of human papillomavirus type 11: Inhibition of the assembly of the E1-E2-Origin DNA complex
Yoakim, Christiane,Ogilvie, William W.,Goudreau, Nathalie,Naud, Julie,Hache, Bruno,O'Meara, Jeff A.,Cordingley, Michael G.,Archambault, Jacques,White, Peter W.
, p. 2539 - 2541 (2007/10/03)
We have discovered a series of inhibitors of the assembly of the HPV11 E1-E2-origin DNA complex, which incorporate an indandione fused to a substituted tetrahydrofuran.
