1273258-31-3

Basic information

• Product Name: 1,4:3,6-dianhydro-2,5-bis-[2-benzamido-(Z)-4-fluorocinnamamido]-2,5-dideoxy-L-iditol
• CAS NO: 1273258-31-3
• Molecular Weight: 678.692
• Mol File: 1273258-31-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,4:3,6-dianhydro-2,5-bis-[2-benzamido-(Z)-4-fluorocinnamamido]-2,5-dideoxy-L-iditol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4:3,6-dianhydro-2,5-bis-[2-benzamido-(Z)-4-fluorocinnamamido]-2,5-dideoxy-L-iditol(1273258-31-3)
• EPA Substance Registry System: 1,4:3,6-dianhydro-2,5-bis-[2-benzamido-(Z)-4-fluorocinnamamido]-2,5-dideoxy-L-iditol(1273258-31-3)

Safety Data

• Hazardous Substances Data: 1273258-31-3(Hazardous Substances Data)

Upstream product

• 449-81-0 (4Z)-2-phenyl-4-[(4-fluorophenyl)methylidene]-1,3-oxazol-5(4H)-one 
• 48107-55-7 2,5-diamino-1,4:3,6-dianhydro-2,5-dideoxy-L-iditol,DAI 

Relevant articles and documents

Pseudo-peptides derived from isomannide: Inhibitors of serine proteases

In this paper, we describe the synthesis of a novel class of pseudo-peptides derived from isomannide and several oxazolones as potential inhibitors of serine proteases as well as preliminary pharmacological assays for hepatitis C. Hepatitis C, dengue and West Nile fever are among the most important flaviviruses that share one important serine protease enzyme. Serine proteases belong to the most studied class of proteolytic enzymes and are a primary target in the drug development field. Several pseudo-peptides were obtained in good yields from the reaction of isomannide and oxazolones, and their anti-HCV potential using the HCV replicon-based assay was shown.