127356-40-5 Usage
Uses
Used in Pharmaceutical Industry:
1-(6-CHLORO-5-NITROPYRIDIN-3-YL)ETHANONE is used as an intermediate in the synthesis of various pharmaceuticals for its strong antibacterial and anti-inflammatory properties, contributing to the development of drugs that address a range of health conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(6-CHLORO-5-NITROPYRIDIN-3-YL)ETHANONE is utilized as an intermediate in the production of agrochemicals, helping to create effective solutions for pest control and crop protection.
Used in Dye and Pigment Manufacturing:
1-(6-CHLORO-5-NITROPYRIDIN-3-YL)ETHANONE is employed as a key component in the manufacturing of dyes and pigments, providing colorants for various industrial applications, including textiles, plastics, and printing inks.
Used in Industrial Applications:
Due to its stability, low volatility, and low solubility in water, 1-(6-CHLORO-5-NITROPYRIDIN-3-YL)ETHANONE is used in a variety of industrial applications where its chemical properties are advantageous for specific processes or end products.
Check Digit Verification of cas no
The CAS Registry Mumber 127356-40-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,3,5 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 127356-40:
(8*1)+(7*2)+(6*7)+(5*3)+(4*5)+(3*6)+(2*4)+(1*0)=125
125 % 10 = 5
So 127356-40-5 is a valid CAS Registry Number.
127356-40-5Relevant academic research and scientific papers
Inotropic 'A' ring substituted sulmazole and isomazole analogues
Barraclough,Black,Cambridge,Collard,Firmin,Gerskowitch,Glen,Giles,Hill,Hull,Iyer,King,Kneen,Lindon,Nobbs,Randall,Shah,Smith,Vine,et al.
, p. 2231 - 2239 (2007/10/02)
A series of 'A' ring substituted sulmazole and isomazole analogues have been prepared and evaluated as inotropic agents. pK(A)'s, protonation sites, and log P values were measured for selected compounds and their electronic properties were calculated. No simple correlation between inotropic activity and pK(A), protonation site, or log P value was observed. However, in vitro inotropism did correlate with the calculated charge density of the 'B' ring imidazo nitrogen atom. The 6-position of sulmazole appeared to be the most tolerant toward substituents, th 6-amino derivative 7 being a more potent inotrope than sulmazole itself. 4-Methoxyisomazole 13 had comparable in vivo inotropic properties to those of isomazole.
