127356-40-5 Usage
General Description
1-(6-chloro-5-nitropyridin-3-yl)ethanone is a chemical compound with the formula C8H6ClN2O3. It is a yellow crystalline solid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 1-(6-CHLORO-5-NITROPYRIDIN-3-YL)ETHANONE is known for its strong antibacterial and anti-inflammatory properties, making it a valuable building block in the production of various drugs. It is also used in the manufacturing of dyes and pigments. Additionally, 1-(6-chloro-5-nitropyridin-3-yl)ethanone is considered to be relatively stable, with low volatility and low solubility in water, making it suitable for a wide range of industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 127356-40-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,3,5 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 127356-40:
(8*1)+(7*2)+(6*7)+(5*3)+(4*5)+(3*6)+(2*4)+(1*0)=125
125 % 10 = 5
So 127356-40-5 is a valid CAS Registry Number.
127356-40-5Relevant articles and documents
Inotropic 'A' ring substituted sulmazole and isomazole analogues
Barraclough,Black,Cambridge,Collard,Firmin,Gerskowitch,Glen,Giles,Hill,Hull,Iyer,King,Kneen,Lindon,Nobbs,Randall,Shah,Smith,Vine,et al.
, p. 2231 - 2239 (2007/10/02)
A series of 'A' ring substituted sulmazole and isomazole analogues have been prepared and evaluated as inotropic agents. pK(A)'s, protonation sites, and log P values were measured for selected compounds and their electronic properties were calculated. No simple correlation between inotropic activity and pK(A), protonation site, or log P value was observed. However, in vitro inotropism did correlate with the calculated charge density of the 'B' ring imidazo nitrogen atom. The 6-position of sulmazole appeared to be the most tolerant toward substituents, th 6-amino derivative 7 being a more potent inotrope than sulmazole itself. 4-Methoxyisomazole 13 had comparable in vivo inotropic properties to those of isomazole.