127372-19-4Relevant academic research and scientific papers
Copper electron-transfer induced trifluoromethylation with methyl fluorosulphonyldifluoroacetate
Chen, Qing-Yun,Yang, Guo-Ying,Wu Sheng-Wen
, p. 291 - 298 (2007/10/02)
Treatment of halogen compounds, RX, with methyl fluorosulfonyldifluoroacetate and copper powder in dimethylformamide for 4 h at 65 - 80 deg C resulted in the corresponding trifluoromethylated products, RCF3, in good yield.In the absence of halogen compounds and at 100 deg C, methyl triflone (CF3SO2CH3) was synthesized readily in the 20 - 30percent yield from the same reaction system.The fact that the reaction was suppressed by oxygen, p-dinitrobenzene or in the darkness suggested that a copper-induced electron-transfer process was involved in this new trifluoromethylating system.
Methyl Fluorosulphonyldifluoroacetate; a New Trifluoromethylating Agent
Chen, Qing-Yun,Wu, Sheng-Wen
, p. 705 - 706 (2007/10/02)
Methyl fluorosulphonyldifluoroacetate, in the presence of copper(I) iodide, is used as the source of trifluoromethyl group which replaces the halogen in aryl, alkenyl, and alkyl halides.
