127422-22-4

Basic information

• Product Name: 3-hydroxy-2-methyl-5-phenyl-pentanethioic acid S-phenyl ester
• Synonyms: 3-hydroxy-2-methyl-5-phenyl-pentanethioic acid S-phenyl ester
• CAS NO: 127422-22-4
• Molecular Weight: 300.422
• Mol File: 127422-22-4.mol

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-2-methyl-5-phenyl-pentanethioic acid S-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-2-methyl-5-phenyl-pentanethioic acid S-phenyl ester(127422-22-4)
• EPA Substance Registry System: 3-hydroxy-2-methyl-5-phenyl-pentanethioic acid S-phenyl ester(127422-22-4)

Safety Data

• Hazardous Substances Data: 127422-22-4(Hazardous Substances Data)

Upstream product

• 108-98-5 thiophenol 
• 104-53-0 3-phenyl-propionaldehyde 
• 30409-97-3 rac-2-methyl-3-oxo-3-(phenylthio)propanoic acid 
• 18245-72-2 S-phenylthiopropionate 

Relevant articles and documents

Stereoelectronic effects dictate mechanistic dichotomy between Cu(II)-catalyzed and enzyme-catalyzed reactions of malonic acid half thioesters

Previously we developed a Cu(II)-catalyzed, enantioselective aldol reaction between malonic acid half thioesters (MAHTs) and aldehydes based on the biosynthesis of polyketides and fatty acids in which MAHTs are decarboxylated enzymatically to afford ester

Catalytic enantioselective thioester aldol reactions that are compatible with protic functional groups

This communication reports highly enantioselective and diastereoselective methyl malonic acid half thioester (MeMAHT) aldol reactions that are compatible with protic functional groups and enolizable aldehydes, affording syn S-phenyl thiopropionates. Copyright