127464-60-2
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Basic information
- Product Name: HUMAN VEGF165
- Synonyms: HUMAN GLIOMA-DERIVED ENDOTHELIAL CELL MITOGEN;HUMAN VEGF;HUMAN VEGF121;HUMAN VEGF165;HUMAN VAS;HUMAN VASCULAR ENDOTHELIAL CELL GROWTH FACTOR;HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR (121 AA);HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR (165 AA)
- CAS NO:127464-60-2
- Molecular Formula: NULL
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: monoclonal antibody
- Mol File: 127464-60-2.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /powder
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: HUMAN VEGF165(CAS DataBase Reference)
- NIST Chemistry Reference: HUMAN VEGF165(127464-60-2)
- EPA Substance Registry System: HUMAN VEGF165(127464-60-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: 22-24/25
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 127464-60-2(Hazardous Substances Data)
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127464-60-2 Usage
Uses
VEGF human has been used as a chemoattractant for HUVECs (human umbilical vein endothelial cells) migration assay.General Description
VEGF (vascular endothelial growth factor) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF is a 38.2kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.Biochem/physiol Actions
VEGF (vascular endothelial growth factor) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intraocular neovascular syndromes. Polymorphism in VEGF at C(-634)G is linked with diabetic retinopathy in type 2 diabetes.Check Digit Verification of cas no
The CAS Registry Mumber 127464-60-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,4,6 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.Calculate Digit Verification of CAS Registry Number 127464-60:
(8*1)+(7*2)+(6*7)+(5*4)+(4*6)+(3*4)+(2*6)+(1*0)=132
132 % 10 = 2
So 127464-60-2 is a valid CAS Registry Number.
127464-60-2Upstream product
127464-60-2Downstream Products
127464-60-2Related news
Expression of HUMAN VEGF165 (cas 127464-60-2) in silkworm (Bombyx mori L.) by using a recombinant baculovirus and its bioactivity assay08/11/2019
Silkworm larva has a lot of advantages as a “biofactory” to produce recombinant protein. A recombinant baculovirus, carrying cDNA encoding the 165 amino-acid long isoform of human vascular endothelial growth factor (VEGF) was successfully constructed for the large-scale production of this prot...detailed
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HUMAN VEGF165
