1274754-64-1

Basic information

• Product Name: S-trityl (2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanethioate
• Synonyms: S-trityl (2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanethioate
• CAS NO: 1274754-64-1
• Molecular Weight: 523.696
• Mol File: 1274754-64-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: S-trityl (2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanethioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-trityl (2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanethioate(1274754-64-1)
• EPA Substance Registry System: S-trityl (2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanethioate(1274754-64-1)

Safety Data

• Hazardous Substances Data: 1274754-64-1(Hazardous Substances Data)

Upstream product

• 3695-77-0 triphenylmethanethiol 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 

Downstream Products

• 120125-43-1 (S)-tert-butyl (1-oxo-3-phenyl-1-(piperidin-1-yl)propan-2-yl)carbamate 

Relevant articles and documents

Fmoc-based synthesis of peptide thioesters for native chemical ligation employing a tert -butyl thiol linker

tert-Butyl thioesters display an astonishing stability toward secondary amines in basic milieu, in contrast to other alkyl and aryl thioesters. Exploiting this enhanced stability, peptide thioesters were synthesized in a direct manner, applying a tert-butyl thiol linker for Fmoc-based solid-phase peptide synthesis.