127478-19-7Relevant academic research and scientific papers
Further studies on 2-arylacetamide pyridazin-3(2H)-ones: Design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists
Giovannoni, Maria Paola,Schepetkin, Igor A.,Cilibrizzi, Agostino,Crocetti, Letizia,Khlebnikov, Andrei I.,Dahlgren, Claes,Graziano, Alessia,Dal Piaz, Vittorio,Kirpotina, Liliya N.,Zerbinati, Serena,Vergelli, Claudia,Quinn, Mark T.
, p. 512 - 528 (2013/07/27)
Formyl peptide receptors (FPRs) play an essential role in the regulation of endogenous inflammation and immunity. In the present studies, a large series of pyridazin-3(2H)-one derivatives bearing an arylacetamide chain at position 2 was synthesized and te
Pyridazines. L . Syntheses and Reactions of Phenyl(3-pyridazinyl)methane Derivatives
Heinisch, Gottfried,Huber, Thierry
, p. 1787 - 1791 (2007/10/02)
A convenient approach to phenyl(3-pyridazinyl)ketone (6) and phenyl(3-pyridazinyl)methanol (7) is proposed.Reactions of the related diarylmethyl chloride 8 with various N- and S-nucleophiles were found to afford the expected amines 9a-c, 10a-c and thioeth
