1274784-85-8

Basic information

• Product Name: C₁₃H₁₃NO₃
• CAS NO: 1274784-85-8
• Molecular Weight: 231.251
• Mol File: 1274784-85-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₃NO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₃NO₃(1274784-85-8)
• EPA Substance Registry System: C₁₃H₁₃NO₃(1274784-85-8)

Safety Data

• Hazardous Substances Data: 1274784-85-8(Hazardous Substances Data)

Upstream product

• 3420-02-8 6-methylindole 
• 4755-77-5 Ethyl oxalyl chloride 
• 64-17-5 ethanol 

Downstream Products

• 1415412-56-4 C₂₅H₂₉NO₆ 

Relevant articles and documents

JAK3 selective inhibitor

The invention discloses a JAK3 selective inhibitor, and relates to a compound represented by formula I/II, or a pharmaceutically acceptable salt thereof. In formula I, Rh, Rg, Rf, m, Re, Rd, Ra, Rb and Rc are as defined in the specification, formula II. The invention also relates to a pharmaceutical composition containing the compound shown in the formula I/II or the pharmaceutically acceptable salt thereof, and applications of the pharmaceutical composition in preparation of drugs for treating inflammation such as rheumatoid arthritis.

Rhodium-catalyzed enantioselective 1,2-addition of arylboronic acids to heteroaryl α-ketoesters for synthesis of heteroaromatic α-hydroxy esters

The first example of catalytic asymmetric 1,2-addition of arylboronic acids to heteroaryl α-ketoesters has been developed for the highly efficient and enantioselective synthesis of quaternary carbon-containing heteroaromatic α-hydroxy esters. The reaction works well with a variety of α-ketoesters including 3-indoleglyoxylates, 3-benzofuranglyoxylates and 3-benzothiopheneglyoxylates under very mild conditions, affording the corresponding products in moderate to good yields with high enantiomeric excesses (up to 97%).