1274940-59-8

Basic information

• Product Name: 5-[[1-[[3-(1,1-dimethylethyl)-phenyl]sulfonyl]-5-trifluoromethyl-1H-indol-2-yl]methyl]-furan-2-carboxylic acid
• Synonyms: 5-[[1-[[3-(1,1-dimethylethyl)-phenyl]sulfonyl]-5-trifluoromethyl-1H-indol-2-yl]methyl]-furan-2-carboxylic acid
• CAS NO: 1274940-59-8
• Molecular Weight: 505.515
• Mol File: 1274940-59-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[[1-[[3-(1,1-dimethylethyl)-phenyl]sulfonyl]-5-trifluoromethyl-1H-indol-2-yl]methyl]-furan-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[[1-[[3-(1,1-dimethylethyl)-phenyl]sulfonyl]-5-trifluoromethyl-1H-indol-2-yl]methyl]-furan-2-carboxylic acid(1274940-59-8)
• EPA Substance Registry System: 5-[[1-[[3-(1,1-dimethylethyl)-phenyl]sulfonyl]-5-trifluoromethyl-1H-indol-2-yl]methyl]-furan-2-carboxylic acid(1274940-59-8)

Safety Data

• Hazardous Substances Data: 1274940-59-8(Hazardous Substances Data)

Upstream product

• 1274940-47-4 [1-[[3-(1,1-dimethylethyl)-phenyl]sulfonyl]-5-trifluoromethyl-1H-indol-2-yl]-methanol 
• 852228-11-6 5-boronofuran-2-carboxylic acid 
• 1274940-52-1 2-bromomethyl-1-[[3-(1,1-dimethylethyl)-phenyl]sulfonyl]-5-trifluoromethyl-1H-indole 
• 1203588-23-1 N-(2-iodo-4-(trifluoromethyl)-phenyl)-3-(1,1-dimethylethyl)-benzene-sulfonamide 

Relevant articles and documents

Use of Indole Derivatives as Nurr-1 Activators for the Application Thereof as a Medicament for the Treatment of Parkinson's Disease

Compounds derived from indole, notably useful in therapeutics, selected from: i) the compounds of formula: and ii) the pharmaceutically acceptable salts of the compounds of formula (I); in which R1, R2, R3, R4, R5, R6, R8, R9 and Cy have defined meanings, and the use of such compounds in pharmaceuticals for the treatment of neurodegenerative diseases, particularly Parkinson's disease.