127500-84-9 Usage
Uses
Used in Pharmaceutical Industry:
RO 41-1049 HCL MAO-A INHIBITOR is used as a therapeutic agent for the treatment of depression, anxiety, and other psychiatric disorders. Its ability to selectively inhibit MAO-A helps to increase the levels of mood-regulating neurotransmitters in the brain, leading to an improvement in mood and a reduction in anxiety symptoms.
Used in Research Applications:
RO 41-1049 HCL MAO-A INHIBITOR is used as a research tool in neuroscience and pharmacology to study the role of MAO-A in the regulation of neurotransmitter levels and its involvement in mood disorders. It helps researchers to understand the mechanisms of action of MAO-A inhibitors and their potential therapeutic effects on various psychiatric conditions.
Used in Drug Development:
RO 41-1049 HCL MAO-A INHIBITOR serves as a lead compound in the development of new drugs targeting MAO-A for the treatment of mood disorders. Its potent and selective inhibition of MAO-A makes it a valuable starting point for the design and optimization of novel therapeutic agents with improved efficacy, safety, and pharmacokinetic properties.
Used in Neuroprotection:
RO 41-1049 HCL MAO-A INHIBITOR may also have potential applications in neuroprotection, as increased levels of neurotransmitters such as dopamine have been associated with neuroprotective effects in certain conditions, including Parkinson's disease. By inhibiting MAO-A, RO 41-1049 HCL could potentially help to maintain or restore neurotransmitter levels, providing neuroprotective benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 127500-84-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,5,0 and 0 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 127500-84:
(8*1)+(7*2)+(6*7)+(5*5)+(4*0)+(3*0)+(2*8)+(1*4)=109
109 % 10 = 9
So 127500-84-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H12FN3OS.ClH/c13-9-3-1-2-8(6-9)11-10(16-7-18-11)12(17)15-5-4-14;/h1-3,6-7H,4-5,14H2,(H,15,17);1H
127500-84-9Relevant academic research and scientific papers
COMPOUNDS FOR TREATING AND PREVENTING COGNITIVE DISEASES AND DEPRESSION AND METHODS OF MAKING SAME
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, (2008/06/13)
Ethylenediamine monoamides of the formula R--CO--NH--CH2 --CH2 --NH2. wherein R is one of groups in which R1 is phenyl monohalophenyl, monolower-alkylphenyl, monolower-alkoxypheynl, monotrifluoromethylphenyl, monocyanophenyl or monoaryl-lower-alkoxyphenyl, dihalophenyl, furyl, thienyl or monohalothienyl, R2 is hydrogen, halogen or amino, R3, R5 and R7 each are phenyl, monohalophenyl, dihalophenyl, thienyl, furyl or monohalofuryl, R4 and R6 each are hydrogen or amino and R8 is hydrogen or lower-alkyl, as well as their pharmaceutically usable acid addition salts are disclosed. The compounds have monoamine oxidase inhibiting properties with low toxicity and are useful for the treatment of depressive states and cognitive disorders
