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CAS

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127515-18-8

(S)-(+)-α-methyl-β-(4-fluorophenyl)-N-methyl-N-propynylethylamine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 127515-18-8 Structure

  • Basic information

    1. Product Name: (S)-(+)-α-methyl-β-(4-fluorophenyl)-N-methyl-N-propynylethylamine
    2. Synonyms: (S)-(+)-α-methyl-β-(4-fluorophenyl)-N-methyl-N-propynylethylamine
    3. CAS NO:127515-18-8
    4. Molecular Formula:
    5. Molecular Weight: 205.275
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 127515-18-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (S)-(+)-α-methyl-β-(4-fluorophenyl)-N-methyl-N-propynylethylamine(CAS DataBase Reference)
    10. NIST Chemistry Reference: (S)-(+)-α-methyl-β-(4-fluorophenyl)-N-methyl-N-propynylethylamine(127515-18-8)
    11. EPA Substance Registry System: (S)-(+)-α-methyl-β-(4-fluorophenyl)-N-methyl-N-propynylethylamine(127515-18-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 127515-18-8(Hazardous Substances Data)

127515-18-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 127515-18-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,5,1 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 127515-18:
(8*1)+(7*2)+(6*7)+(5*5)+(4*1)+(3*5)+(2*1)+(1*8)=118
118 % 10 = 8
So 127515-18-8 is a valid CAS Registry Number.

127515-18-8Downstream Products

127515-18-8Relevant articles and documents

Synthesis of (R)-(-)- and (S)-(+)-4-fluorodeprenyl and (R)-(-)- and (S)-(+)-[N-11C-methyl]-4-fluorodeprenyl and positron emission tomography studies in baboon brain

Plenevaux,Dewey,Fowler,Guillaume,Wolf

, p. 2015 - 2019 (1990)

(R)-(-)- and (S)-(+)-α-methyl-β-4-(fluorophenyl)-N-methyl-N-propynylethylamine ((R)-(-)- and (S)-(+)-4-fluorodeprenyl) were synthesized via the reaction of 4-fluorobenzaldehyde with nitroethane followed by reduction with lithium aluminum hydride to produce racemic 4-fluoroamphetamine, which was resolved by recrystallization with L- or D-N-acetylleucine to yield (R)-(-)-4-fluoroamphetamine or (S)-(+)-4-fluoroamphetamine in >96% enantiomeric excesses and in yields of 42 and 39%, respectively. Alkylation with propargyl bromide gave (R)-(-)- or (S)-(+)-4-fluoronordeprenyl which was reductively methylated (Borch conditions) to produce (R)-(-)- or (S)-(+)-4-fluorodeprenyl. Alkylation of (R)-(-)- or (S)-(+)-4-fluoronordeprenyl with carbon-11 labeled methyl iodide gave (R)-(-)- or (S)-(+)-[N-11C-methyl]-4-fluorodeprenyl in a radiochemical yield of 30-40%. Comparative PET studies of the two labeled enantiomers in baboons showed a significantly lower retention of radioactivity in the striatum for the (S)-(+) enantiomer relative to the (R)-(-) enantiomer.

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