127515-30-4 Usage
General Description
2-amino-4,5-methanoadipate is a chemical compound that belongs to the class of alpha-amino acids and derivatives. It is a naturally occurring compound that is found in certain microorganisms and plants, and it plays a key role in the biosynthesis of various important molecules, including the amino acid lysine. It is also known to exhibit antioxidant properties and has been studied for its potential therapeutic applications in the treatment of various diseases. Additionally, 2-amino-4,5-methanoadipate has been investigated for its potential use in various industrial applications, such as in the production of bio-based polymers and other materials. Overall, this compound has garnered significant interest in the scientific community due to its diverse biological and industrial potential.
Check Digit Verification of cas no
The CAS Registry Mumber 127515-30-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,5,1 and 5 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 127515-30:
(8*1)+(7*2)+(6*7)+(5*5)+(4*1)+(3*5)+(2*3)+(1*0)=114
114 % 10 = 4
So 127515-30-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H11NO4/c8-5(7(11)12)2-3-1-4(3)6(9)10/h3-5H,1-2,8H2,(H,9,10)(H,11,12)
127515-30-4Relevant articles and documents
Synthesis, absolute configuration and activity at N-methyl-D-aspartic acid (NMDA) receptor of the four D-2-amino-4,5-methano-adipate diastereoisomers
Pellicciari,Natalini,Marinozzi,Sadeghpour,Cordi,Lanthorn,Hood,Monahan
, p. 1243 - 1264 (2007/10/02)
The four D-2-amino-4,5-methano-adipates 26, 27, 32, 33 were synthesized and their biological activity at the N-methyl-D-aspartate (NMDA) receptor was assessed. The synthesis involved as a key step a rhodium acetate dimer catalyzed addition of ethyl diazoacetate to the protected D-allylglycine (17). In vitro receptor binding using L-[3H]glutamate as the radioligand provided affinity data, while modulation of [3H]TCP binding was used as a functional assay. The analogues were also evaluated in [3H]kainate and [3H]AMPA binding to assess selectivity over non-NMDA glutamate receptors. Three of the four diastereoisomer, D-CAA B (27), C (32) and D (33) were shown to have agonist properties at the NMDA-site, while the fourth, (2R,4R,5R) D-CAA A (26) was characterized as an NMDA-site atypic antagonist.
