Welcome to LookChem.com Sign In|Join Free

CAS

  • or

127516-98-7

Post Buying Request

127516-98-7 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

127516-98-7 Usage

General Description

The chemical compound "(1E)-1,2-dideoxy-1-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-D-erythro-pent-1-enitol" is a derivative of D-erythro-pent-1-enitol that contains a dideoxy group and a 5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl) moiety. (1E)-1,2-dideoxy-1-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-D-erythro-pent-1-enitol has potential biological activity and may be of interest in pharmaceutical research. Its precise properties and potential applications would require further study, including testing for its safety and efficacy for specific medicinal or industrial purposes.

Check Digit Verification of cas no

The CAS Registry Mumber 127516-98-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,5,1 and 6 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 127516-98:
(8*1)+(7*2)+(6*7)+(5*5)+(4*1)+(3*6)+(2*9)+(1*8)=137
137 % 10 = 7
So 127516-98-7 is a valid CAS Registry Number.

127516-98-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methyl-1-[(E,3S,4R)-3,4,5-trihydroxypent-1-enyl]pyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127516-98-7 SDS

127516-98-7Upstream product

127516-98-7Downstream Products

127516-98-7Relevant articles and documents

Synthesis and Anti-HIV Evaluation of 2',3'-Dideoxyribo-5-chloropyrimidine Analogues: Reduced Toxicity of 5-Chlorinated 2',3'-Dideoxynucleosides

Aerschot, Arthur Van,Everaert, Dirk,Balzarini, Jan,Augustyns, Koen,Jie, Liu,at al.

, p. 1833 - 1839 (2007/10/02)

In view of the selective anti-HIV activity of 2',3'-dideoxy-3'-fluoro-5-chlorouridine (11), a series of eight 2',3'-dideoxy-5-chloropyrimidines were synthesized and evaluated for their inhibitory activity against human immunodeficiency virus type 1 (HIV-1) replication in MT-4 cells.A marked improvement in selectivity was noted for the 5-chlorouracil derivatives of 2,3-dideoxyribofuranose, 3-azido-2,3-dideoxyribofuranose, and 3-fluoro-2,3-dideoxyribofuranose, mainly due to decreased toxicity of the compounds for the host cells.While chlorination of 2',3'-dideoxycytidine remo ved the anti-HIV activity, introduction of chlorine at the C-5 position of 3'-fluoro-, 3'-azido- or 2',3'-didehydro-2',3'-dideoxycytidine led to reduced cytotoxicity with only slightly reduced anti-HIV activity.X-ray analysis showed compound 11 to have two molecules in the asymmetric unit with κ = -168.8(3) deg and -131.3(3) deg and P = 179(1) deg and 163(1) deg, respectively; thus revealing no close resemblance to 3'-azido-3'-deoxythymidine (AZT).

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 127516-98-7