127530-30-7

Upstream product

• 443-26-5 2-fluoro-benzoic acid ethyl ester 
• 394-35-4 methyl 2-fluorobenzoate 

Downstream Products

• 107135-17-1 2-fluoro-<α-²H>benzaldehyde 
• 107135-16-0 α-deuterio-o-fluorobenzaldehyde tosylhydrazone 
• 185435-44-3 3-(2-{[(tert-butyldimethylsilyl)oxy][²H₂]methyl}phenyl)-10-(4-tert-butylphenyl)[5-²H]pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione 
• 1026501-87-0 C₂₈H₂₄⁽²⁾H₃N₃O₃ 
• 185435-45-4 10-(4-tert-butylphenyl)-3-[2-(trifluoromethyl)phenyl][5-²H]pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione 
• 185435-43-2 10-(4-tert-butylphenyl)-3-(2-methylphenyl)[5-²H]pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione 

Relevant academic research and scientific papers

Supersonic Jet Studies of Benzyl Alcohols: Minimum Energy Conformations and Torsional Motion

Supersonic jet mass resolved excitation spectroscopy is employed to determine the minimum energy conformations of benzyl alcohol and a series of nine methyl-, ethyl-, fluoro-, and aminobenzyl alcohols. The interpretation of the mass resolved excitation sp

Reductive Deuteration of Aromatic Esters for the Synthesis of α,α-Dideuterio Benzyl Alcohols Using D 2O as Deuterium Source

α,α-Dideuterio benzyl alcohols are important building blocks for the synthesis of deuterium-labeled medicines and agrochemicals. We have developed the first general single-electron transfer reductive deuteration of readily commercially available aromatic

An α, α - dideuterium substituted benzyl alcohol compound. Deuterated drug and method for reducing deuteration of benzoate compound

The invention relates to a method. Α, α-deuterated benzyl alcohol compound and preparation thereofΑ, αThe method for reducing and deuteration - dideuterium-substituted benzyl alcohol compounds is characterized in that the benzoate compound represented by

Atropisomeric flavoenzyme models with a modified pyrimidine ring: Syntheses, physical properties, and stereochemistry, in the reactions with NAD(P)H analogs

Optically active 5-deazaflavin derivatives (3-aryl-10-(4-tert-butylphenyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-di one) with an axial chirality at the pyrimidine ring have been synthesized, and the kinetics of enantiomerization have been measured for some

1,2,4,6-CYCLOHEPTATETRAENE: THE KEY INTERMEDIATE IN ARYLCARBENE INTERCONVERSIONS AND RELATED C7H6 REARRANGEMENTS

Thermolysis or photolysis of phenyldiazomethane (2) produces phenylmethylene (3), which ring-expands to give 1,2,4,6-cycloheptatetraene (6).Spectroscopic and chemical evidence rule out bicyclo(4.1.0)hepta-2,4,6-triene (4), cycloheptatrienylidene (5), and bicyclo(3.2.0)hepta-1,3,6-triene (11) intermediates.The strained allene in cycloheptatetraene (6) exhibits infrared absorption at 1824 and 1816 cm-1.Deuterium substitution produces the expected 10-cm-1 shift in the allene absorption.Fluorine or chlorine substitution substantially enhances the allene absorption intensity.Deuterium labeling studies reveal that the intramolecular chemistry of cycloheptatetraene (6) involves reversible thermal or photochemical equilibriation with phenylmethylene (3).The intermolecular chemistry of 6 involves dimerization.At temperatures as low as 10 K, 6 forms a labile (2+2) dimer,7, which undergoes thermally allowed, electrocyclic ring opening to give heptafulvalene (8) upon warming to room temperature.The rearrangements of 7-acetoxynorbornadiene (9), 2-diazobicyclo(3.2.0)hepta-3,6-diene (31), and 8-diazobicyclo(2.2.2)octa-2,5-dien-7-one (33) all involve cycloheptatetraene (6) intermediates.