1275596-57-0Relevant articles and documents
Synthesis of bi-substrate state mimics of dihydropteroate synthase as potential inhibitors and molecular probes
Qi, Jianjun,Virga, Kristopher G.,Das, Sourav,Zhao, Ying,Yun, Mi-Kyung,White, Stephen W.,Lee, Richard E.
, p. 1298 - 1305 (2011)
The increasing emergence of resistant bacteria drives us to design and develop new antimicrobial agents. Pursuant to that goal, a new targeting approach of the dihydropteroate synthase enzyme, which serves as the site of action for the sulfonamide class o