127582-76-7 Usage
Description
Fmoc-7-amino-heptanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical Properties
White powder
Uses
7-(Fmoc-amino)heptanoic acid is used as pharmaceutical intermediates.
Check Digit Verification of cas no
The CAS Registry Mumber 127582-76-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,5,8 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 127582-76:
(8*1)+(7*2)+(6*7)+(5*5)+(4*8)+(3*2)+(2*7)+(1*6)=147
147 % 10 = 7
So 127582-76-7 is a valid CAS Registry Number.
InChI:InChI=1/C22H25NO4/c24-21(25)13-3-1-2-8-14-23-22(26)27-15-20-18-11-6-4-9-16(18)17-10-5-7-12-19(17)20/h4-7,9-12,20H,1-3,8,13-15H2,(H,23,26)(H,24,25)