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4-(3-thioxo-3H-1,2-dithiol-4-yl)benzoic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 127588-56-1 Structure
  • Basic information

    1. Product Name: 4-(3-thioxo-3H-1,2-dithiol-4-yl)benzoic acid
    2. Synonyms: 4-(3-thioxo-3H-1,2-dithiol-4-yl)benzoic acid
    3. CAS NO:127588-56-1
    4. Molecular Formula:
    5. Molecular Weight: 254.354
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 127588-56-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(3-thioxo-3H-1,2-dithiol-4-yl)benzoic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(3-thioxo-3H-1,2-dithiol-4-yl)benzoic acid(127588-56-1)
    11. EPA Substance Registry System: 4-(3-thioxo-3H-1,2-dithiol-4-yl)benzoic acid(127588-56-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 127588-56-1(Hazardous Substances Data)

127588-56-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 127588-56-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,5,8 and 8 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 127588-56:
(8*1)+(7*2)+(6*7)+(5*5)+(4*8)+(3*8)+(2*5)+(1*6)=161
161 % 10 = 1
So 127588-56-1 is a valid CAS Registry Number.

127588-56-1Relevant articles and documents

New aryldithiolethione derivatives as potent histone deacetylase inhibitors

Tazzari, Valerio,Cappelletti, Graziella,Casagrande, Manolo,Perrino, Elena,Renzi, Luigi,Del Soldato, Piero,Sparatore, Anna

experimental part, p. 4187 - 4194 (2010/09/12)

A series of dithiolethione derivatives was synthesized and the in vitro HDAC inhibitory activity was tested. The most active compounds, 1 and 2, exhibited an IC50 in nM range with a strong hyperacetylation of histone H4 in A549 cells. The HDAC

NEW AGENTS FOR THE TREATMENT OF THE LOW URINARY TRACT DYSFUNCTIONS

-

, (2009/04/25)

The present invention relates to novel compounds that are derivatives of 5 -phosphodiesterase inhibitors that comprise in their formula a polysulfurated group and that are useful for treating dysfunctions of low urinary tract such as incontinence, benign prostatic hyperplasia and erectile dysfunction.

NEW ANTICANCER COMPOUNDS

-

Page/Page column 23, (2009/06/27)

The present invention relates to new polysulf urated compounds containing 2 or more sulphur atoms belonging to the class of organic thiosulf onates, or dithiole-thione derivatives cyclic or linear, or trithiocarbonates for the use alone or in combination with other anticancer treatments for the treatment and/or prevention of cancer and inflammatory diseases.

OCULAR PHARMACEUTICAL COMPOSITIONS

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Page/Page column 21-23, (2009/10/22)

The present invention relates to novel derivatives of opthalmic compounds for the treatment of ocular diseases.

Cardiovascular agents

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Page/Page column 8-9, (2008/12/04)

The present invention relates to novel compounds that are derivatives of angiotensin receptor blocker (ARB) that comprise in their formula a polysulfurated group and that are useful for treating cardio-vascular diseases, such as hypertension, ischemic heart disease, atherosclerosis, metabolic syndrome, etc. also in combination with other cardiovascular agents.

N2S2 tetradentate ligands for soft cationic species: preparation of new ligands of potential interest in nuclear medicine

Charbonnel-Jobic, Gaelle,Guemas, Jean-Pierre,Adelaere, Bruno,Parrain, Jean-Luc,Quintard, Jean-Paul

, p. 624 - 636 (2007/10/02)

The synthesis of N2S2 tetradentate ligands of the bis-(enaminothioester) type was carried out starting from 3-(methylthio)-3H-1,2-dithiolylium iodides and diamines.The title compounds, which are potential ligands for soft cationic species, can be obtained from 1,3-diaminopropan-2-ol and subsequently modified into the dissymmetrical succinic acid ester of the ligand and N-hydroxysuccinimide.The appendage of such a linking group on the chelating structure should allow further grafting to monoclonal antibodies in view of potential applications in nuclear medicine. 3H-1,2-dithiole-3-thione / 1,3-diaminopropan-2-ol / bis-(enaminothioester) / N2S2 tetradentate ligand / N-hydroxysuccinimidyl ester

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