127592-76-1 Usage
Description
(S)-2-amino-3-(1H-indole-3-yl)-N-phenylpropionamide, also known as L-tryptophan amide or α-methyltryptophan amide, is a complex chemical compound that belongs to the amino acid group. It is a chiral molecule with an amine and a carboxylic acid functional group, as well as a phenyl and an indole group. (S)-2-amino-3-(1H-indole-3-yl)-N-phenylpropionamide plays a crucial role in the biosynthesis of proteins, neurotransmitters, and other biologically active molecules in living organisms.
Uses
Used in Pharmaceutical Industry:
(S)-2-amino-3-(1H-indole-3-yl)-N-phenylpropionamide is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Biochemical Research:
In the field of biochemistry, (S)-2-amino-3-(1H-indole-3-yl)-N-phenylpropionamide serves as an important research tool for studying the mechanisms of protein synthesis, enzyme catalysis, and other biological processes. Its involvement in the biosynthesis of neurotransmitters also makes it a valuable compound for investigating the role of these molecules in the nervous system.
Used in Agrochemical Industry:
(S)-2-amino-3-(1H-indole-3-yl)-N-phenylpropionamide has potential applications in the agrochemical industry, where it can be utilized as a precursor for the synthesis of bioactive molecules with pesticidal, herbicidal, or plant growth-regulating properties. Its unique structure and functional groups make it a promising candidate for the development of novel agrochemicals with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 127592-76-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,5,9 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 127592-76:
(8*1)+(7*2)+(6*7)+(5*5)+(4*9)+(3*2)+(2*7)+(1*6)=151
151 % 10 = 1
So 127592-76-1 is a valid CAS Registry Number.
127592-76-1Relevant articles and documents
Synthetic process of chiral N-aromatic amino acid amide
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Paragraph 0010; 0014, (2016/10/17)
Chiral N-aromatic amino acid amide is a core structure fragment of drugs and an intermediate of the drugs. Only if the chiral structure of the product is not required by special raw materials such aryl halide activated by functional groups of nitryl and t
C ring may be dispensable for β-carboline: Design, synthesis, and bioactivities evaluation of tryptophan analog derivatives based on the biosynthesis of β-carboline alkaloids
Huang, Yuanqiong,Liu, Yongxian,Liu, Yuxiu,Song, Hongjian,Wang, Qingmin
, p. 462 - 473 (2016/01/25)
According to our previous work and the latest research on the biosynthesis of β-carboline, and using the reverse thinking strategy, tryptophan, the biosynthesis precursor of β-carboline alkaloids, and their derivatives were synthesized, and their biological activities and structure-activity relationships were studied. This bioassay showed that these compounds exhibited good inhibitory activities against tobacco mosaic virus (TMV); especially (S)-2-amino-3-(1H-indol-3-yl)-N-octylpropanamide (4) (63.3 ± 2.1%, 67.1 ± 1.9%, 68.7 ± 1.3%, and 64.5 ± 3.1%, 500 μg/mL) exhibited the best antiviral activity both in vitro and in vivo. Compound 4 was chosen for the field trials and the acute oral toxicity test, the results showed that the compound exhibited good anti-TMV activity in the field and low acute oral toxicity. We also found that these compounds showed antifungal activities and insecticidal activities.
Organocatalysis of asymmetric aldol reaction in water: Comparison of catalytic properties of (S)-valine and (S)-proline amides
Kucherenko,Siyutkin,Dashkin,Zlotin
, p. 1010 - 1015 (2014/03/21)
(S)-Valine amides containing (S)- or (R)-α-phenylethyl substituents at N1 atom efficiently catalyze asymmetric aldol reactions between cyclic (heterocyclic) ketones and aromatic aldehydes in water, predominantly giving rise to the aldol anti-di
