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Relevant academic research and scientific papers

Diphenylamine-amine-oxazoline ligand, synthesis method as well as metal complex and application thereof

The invention provides a diphenylamine-amine-oxazoline ligand which is a compound of formula (1) or an antipode or racemate of the compound of formula (1), wherein R1 and R2 are respectively and separately one of C1 to C10 hydrocarbon group, benzyl group, phenyl group or substituted phenyl group and heteroaryl group; and R3 is H or methyl. The invention also discloses a synthesis method as well asa metal complex and application thereof, which aims at providing a catalyst capable of realizing high synthesis yield by virtue of a simple synthesis route, and ensuring that the catalyst has very high catalytic activity in asymmetric hydrogenation and hydrogen transfer reactions of olefins and ketones.

Manganese-Catalyzed Transfer Hydrogenation of Aldimines

The reduction of imines to amines via transfer hydrogenation was achieved promoted by phosphine-free manganese(I) catalyst. Using isopropanol as reductant, in the presence of tBuOK (4 mol %) and manganese complex [Mn(CO)3Br(κ2N,N-PyCH2NH2)] (2 mol %), a large variety of aldimines (30 examples) were typically reduced in 3 hours at 80 °C with good to excellent yield.

Cobalt(II) phthalocyanine-catalyzed highly chemoselective reductive amination of carbonyl compounds in a green solvent

Cobalt phthalocyanine has been employed for the highly chemoselective reductive amination of aldehydes and ketones in ethanol as a green solvent. A large range of functional groups such as nitro, acid, amide, ester, nitrile, halogen, lactone, methoxy, hydroxy, alkene, N-benzyl, O-benzyl and heterocyclic rings were well tolerated under the present reaction conditions. Copyright